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Zfp980 zinc finger protein 980 [ Mus musculus (house mouse) ]

Gene ID: 100041379, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp980provided by MGI
Official Full Name
zinc finger protein 980provided by MGI
Primary source
MGI:MGI:3712454
See related
Ensembl:ENSMUSG00000058186 AllianceGenome:MGI:3712454
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13242
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in nucleus. Is expressed in epiblast; primitive endoderm; and trophectoderm. Orthologous to human ZNF616 (zinc finger protein 616). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Zfp980 in Genome Data Viewer
Location:
4 E1; 4 78.23 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (145397267..145431007)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (145670697..145704437)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr4:145243801-145244102 Neighboring gene predicted gene 13249 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145254570-145254871 Neighboring gene STARR-seq mESC enhancer starr_12035 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145269028-145269328 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145271302-145271602 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145274293-145274594 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145275073-145275374 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145276526-145276827 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145276879-145277180 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145277691-145277992 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145278790-145279091 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145281441-145281742 Neighboring gene high mobility group box 3 pseudogene Neighboring gene vomeronasal 2, receptor, pseudogene 15 Neighboring gene predicted gene, 26763 Neighboring gene predicted gene 13232

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. Dietrich JE, et al. EMBO Rep, 2015 Aug. PMID 26142281, Free PMC Article
  2. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  3. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  4. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  5. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Clone Names

  • MGC106319

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC100041379

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103158.2 → NP_001096628.2  uncharacterized protein LOC100041379

    Status: VALIDATED

    Source sequence(s)
    BC096593, CD539619
    Consensus CDS
    CCDS51370.1
    UniProtKB/TrEMBL
    A2A9J5
    Related
    ENSMUSP00000101364.3, ENSMUST00000105738.9
    Conserved Domains (5) summary
    smart00349
    Location:28 → 70
    KRAB; krueppel associated box
    COG5048
    Location:96 → 510
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:253 → 273
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:28 → 67
    KRAB; KRAB box
    pfam13465
    Location:602 → 626
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    145397267..145431007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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