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Sprr2a3 small proline-rich protein 2A3 [ Mus musculus (house mouse) ]

Gene ID: 100042514, updated on 2-Nov-2024

Summary

Official Symbol
Sprr2a3provided by MGI
Official Full Name
small proline-rich protein 2A3provided by MGI
Primary source
MGI:MGI:3845028
See related
Ensembl:ENSMUSG00000074445 AllianceGenome:MGI:3845028
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sprr2a; Sprr2a1
Summary
Predicted to enable lipid binding activity. Involved in defense response to Gram-positive bacterium. Is active in extracellular region and secretory granule. Is expressed in stomach and thymus primordium. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in stomach adult (RPKM 7615.5), small intestine adult (RPKM 5309.9) and 4 other tissues See more
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Genomic context

See Sprr2a3 in Genome Data Viewer
Location:
3 F1; 3 40.14 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (92192611..92196571)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (92285304..92289264)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene small proline-rich protein 2A2 Neighboring gene STARR-positive B cell enhancer mm9_chr3:92069949-92070249 Neighboring gene STARR-positive B cell enhancer mm9_chr3:92070431-92070732 Neighboring gene STARR-positive B cell enhancer mm9_chr3:92071949-92072250 Neighboring gene ribosomal protein L3 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr3:92074536-92074836 Neighboring gene STARR-positive B cell enhancer mm9_chr3:92080442-92080742 Neighboring gene STARR-seq mESC enhancer starr_08311 Neighboring gene small proline-rich protein 2B Neighboring gene small proline-rich protein 2C, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC117544

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cornified envelope IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in secretory granule IDA
Inferred from Direct Assay
more info
PubMed 
located_in transport vesicle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small proline-rich protein 2A3
Names
Small proline-rich protein 2A1
small proline-rich protein 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001309382.1NP_001296311.1  small proline-rich protein 2A3

    See identical proteins and their annotated locations for NP_001296311.1

    Status: VALIDATED

    Source sequence(s)
    AC129296, BY094335, EH096608, EH099857, EH102273
    Consensus CDS
    CCDS84652.1
    UniProtKB/Swiss-Prot
    O70553, Q4KL71, Q9CQK8
    Related
    ENSMUSP00000142110.2, ENSMUST00000193337.2
    Conserved Domains (1) summary
    pfam14820
    Location:283
    SPRR2; Small proline-rich 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    92192611..92196571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)