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Il11ra3 interleukin 11 receptor subunit alpha 3 [ Mus musculus (house mouse) ]

Gene ID: 100042555, updated on 2-Nov-2024

Summary

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Official Symbol
Il11ra3provided by MGI
Official Full Name
interleukin 11 receptor subunit alpha 3provided by MGI
Primary source
MGI:MGI:3801997
See related
Ensembl:ENSMUSG00000073876 AllianceGenome:MGI:3801997
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm2002; Gm13305
Summary
Predicted to enable interleukin-11 receptor activity. Predicted to be involved in embryo implantation; head development; and interleukin-11-mediated signaling pathway. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 25.3), limb E14.5 (RPKM 24.4) and 28 other tissues See more
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Genomic context

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See Il11ra3 in Genome Data Viewer
Location:
4 A5; 4 22.5 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (42158842..42168603, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (42158842..42168603, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine ligand 21F Neighboring gene C-C motif chemokine ligand 19, pseudogene 3 Neighboring gene C-C motif chemokine ligand 27A like Neighboring gene predicted gene, 53181 Neighboring gene C-C motif chemokine ligand 21B (leucine) Neighboring gene STARR-seq mESC enhancer starr_10038 Neighboring gene STARR-seq mESC enhancer starr_10039 Neighboring gene STARR-seq mESC enhancer starr_10040 Neighboring gene family with sequence similarity 205 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Modernizing reference genome assemblies. Church DM, et al. PLoS Biol, 2011 Jul. PMID 21750661, Free PMC Article
  2. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC164180, MGC170217, MGC178905

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables interleukin-11 receptor activity ISO
Inferred from Sequence Orthology
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in developmental process ISO
Inferred from Sequence Orthology
more info
  
involved_in embryo implantation ISO
Inferred from Sequence Orthology
more info
  
involved_in head development ISO
Inferred from Sequence Orthology
more info
  
involved_in interleukin-11-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
interleukin 11 receptor, alpha chain 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099348.1 → NP_001092818.1  interleukin 11 receptor, alpha chain 2-like isoform 1 precursor

    See identical proteins and their annotated locations for NP_001092818.1

    Status: VALIDATED

    Source sequence(s)
    AL824709
    Consensus CDS
    CCDS51150.1
    UniProtKB/Swiss-Prot
    A2RTL4, B1AXR8, O09074, P70225, Q78DW8
    UniProtKB/TrEMBL
    Q3UIV4
    Related
    ENSMUSP00000095725.4, ENSMUST00000098121.4
    Conserved Domains (4) summary
    smart00410
    Location:33 → 95
    IG_like; Immunoglobulin like
    cd00063
    Location:218 → 310
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:35 → 98
    Ig; Immunoglobulin domain
    cl21522
    Location:112 → 202
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. NM_001378674.1 → NP_001365603.1  interleukin 11 receptor, alpha chain 2-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL824709
    UniProtKB/TrEMBL
    Q3UIV4
    Conserved Domains (2) summary
    smart00409
    Location:45 → 107
    IG; Immunoglobulin
    cd00063
    Location:230 → 322
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    42158842..42168603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163530.1 → XP_036019423.1  interleukin 11 receptor, alpha chain 2-like isoform X2

    UniProtKB/TrEMBL
    Q3UIV4
    Conserved Domains (2) summary
    smart00409
    Location:37 → 99
    IG; Immunoglobulin
    cd00063
    Location:222 → 314
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein Strain
Heading Accession and Version

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