GAGE8 G antigen 8 [Homo sapiens (human)] - Gene

Summary

Official Symbol: GAGE8provided by HGNC
Official Full Name: G antigen 8provided by HGNC
Primary source: HGNC:HGNC:4106
See related: MIM:300638
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: CT4.8; GAGE-8
Summary: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Annotation information: not in current annotation release
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Genomic context

Location:: Xp11

Annotation release	Status	Assembly	Chr	Location
105.20220307	latest, but not current	GRCh37.p13 (GCF_000001405.25)	X	NC_000023.10 (49197607..49204923)

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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See variants in ClinVar

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See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:481091

NoName (e-PCR)
- UniSTS:481101

NoName (e-PCR)
- UniSTS:482134

NoName (e-PCR)
- UniSTS:487065

NoName (e-PCR)
- UniSTS:494525

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: G antigen 2D

Names: cancer/testis antigen 4.8; cancer/testis antigen family 4, member 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.