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KIR3DS05 killer immunoglobulin-like receptor KIR [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 100125571, updated on 18-Aug-2023

Summary

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Gene symbol
KIR3DS05
Gene description
killer immunoglobulin-like receptor KIR
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
KIR; 3DS05; *008:01; *008:02; KIR-3DS; KIR3DH1; KIR3DS06; Mamu-KIR
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Genomic context

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See KIR3DS05 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (54566306..54579164)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) Unplaced Scaffold NW_015071847.1 (1060..1353, complement)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene putative killer cell immunoglobulin-like receptor like protein KIR3DP1 Neighboring gene killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Neighboring gene killer-cell Ig-like receptor KIR3DL12 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys. Hellmann I, et al. PLoS Pathog, 2011 Dec. PMID 22194686, Free PMC Article
  2. Characterization of rhesus macaque KIR genotypes and haplotypes. Kruse PH, et al. Immunogenetics, 2010 May. PMID 20195593
  3. Multiple KIR gene polymorphisms are associated with plasma viral loads in SIV-infected rhesus macaques. Chaichompoo P, et al. Cell Immunol, 2010. PMID 20430371, Free PMC Article
  4. A splice site mutation converts an inhibitory killer cell Ig-like receptor into an activating one. Blokhuis JH, et al. Mol Immunol, 2009 Feb. PMID 19019442
  5. KIR3DL01 upregulation on gut natural killer cells in response to SIV infection of KIR- and MHC class I-defined rhesus macaques. Ries M, et al. PLoS Pathog, 2017 Jul. PMID 28708886, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. select KIR3DH alleles appear to be more strongly associated with high plasma viral loads than KIR3DL alleles 13 and 14
    Title: Multiple KIR gene polymorphisms are associated with plasma viral loads in SIV-infected rhesus macaques.
  2. Within the present panel of 19 animals, covering four families, a total of 70 different KIR sequences were observed, 49 of which have not been reported before in the scientific literature.
    Title: The mosaic of KIR haplotypes in rhesus macaques.
  3. Segregation analyses of KIR genes and of two polymorphic microsatellite markers allowed the identification of 21 distinct KIR haplotypes in these families, with five to 11 segregating KIR genes per haplotype.
    Title: Characterization of rhesus macaque KIR genotypes and haplotypes.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

General protein information

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Preferred Names
killer immunoglobulin-like receptor KIR
Names
KIR-3DS05 protein
KIR3DS protein
Mamu-KIR3DS05
killer cell immunoglobulin-like receptor KIR3DM1
killer cell immunoglobulin-like receptor KIR3DM6
killer immunoglobulin-like receptor 3DS
natural killer cell activating receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001246254.1 → NP_001233183.1  killer immunoglobulin-like receptor KIR precursor

    See identical proteins and their annotated locations for NP_001233183.1

    Status: PROVISIONAL

    Source sequence(s)
    GU263420
    UniProtKB/TrEMBL
    A0A3F2XHN1, A0A6F8ZCB1
    Conserved Domains (3) summary
    cd00096
    Location:124 → 128
    Ig; Ig strand A [structural motif]
    cd05711
    Location:30 → 117
    IgC2_D2_LILR_KIR_like; Second immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors, Natural killer inhibitory receptors (KIRs) and similar domains; member of Immunoglobulin Constant-2 set of IgSF domains
    cl11960
    Location:123 → 217
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    54566306..54579164
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials