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TRIM5 tripartite motif containing 5 [ Papio anubis (olive baboon) ]

Gene ID: 100126714, updated on 8-Mar-2024

Summary

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Gene symbol
TRIM5
Gene description
tripartite motif containing 5
See related
Ensembl:ENSPANG00000023175
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Papio anubis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Orthologs
human all
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Genomic context

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See TRIM5 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
104 current Panubis1.0 (GCF_008728515.1) 12 NC_044987.1 (64870580..64898198)
103 previous assembly Panu_3.0 (GCF_000264685.3) 14 NC_018165.2 (59816922..59844530)

Chromosome 12 - NC_044987.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 651 Neighboring gene tripartite motif containing 22 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene tripartite motif containing 34

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of the antiretroviral restriction factor TRIMCyp in Old World primates. Dietrich EA, et al. PLoS One, 2010 Nov 16. PMID 21103414, Free PMC Article
  2. Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Sawyer SL, et al. Proc Natl Acad Sci U S A, 2005 Feb 22. PMID 15689398, Free PMC Article
  3. Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Kaiser SM, et al. Science, 2007 Jun 22. PMID 17588933
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tripartite motif-containing protein 5
Names
RING-type E3 ubiquitin transferase TRIM5
TRIM5alpha
tripartite motif-containing 5 alpha
NP_001106102.1
XP_009185022.2
XP_017803568.2
XP_021780990.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001112632.1 → NP_001106102.1  tripartite motif-containing protein 5

    See identical proteins and their annotated locations for NP_001106102.1

    Status: PROVISIONAL

    Source sequence(s)
    EF551342
    UniProtKB/Swiss-Prot
    Q5D7J2
    UniProtKB/TrEMBL
    A7U0P5, E5FGA9
    Related
    ENSPANP00000005557.2, ENSPANT00000016421.3
    Conserved Domains (3) summary
    cd00021
    Location:95 → 133
    BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
    cd00162
    Location:14 → 60
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd15822
    Location:290 → 493
    SPRY_PRY_TRIM5; PRY/SPRY domain in tripartite motif-binding protein 5 (TRIM5), also known as RING finger protein 88 (RNF88)

RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Panubis1.0 Primary Assembly

Genomic

  1. NC_044987.1 Reference Panubis1.0 Primary Assembly

    Range
    64870580..64898198
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009186758.4 → XP_009185022.2  tripartite motif-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A096MZZ7, E5FGA9
    Related
    ENSPANP00000041876.2, ENSPANT00000051528.2
    Conserved Domains (4) summary
    pfam05483
    Location:64 → 265
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    cd15822
    Location:290 → 493
    SPRY_PRY_TRIM5; PRY/SPRY domain in tripartite motif-binding protein 5 (TRIM5), also known as RING finger protein 88 (RNF88)
    cd16591
    Location:12 → 61
    RING-HC_TRIM5_like-C-IV; RING finger, HC subclass, found in tripartite motif-containing proteins TRIM5, TRIM6, TRIM22, TRIM34 and similar proteins
    cd19761
    Location:95 → 134
    Bbox2_TRIM5-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM5, TRIM6, TRIM22, TRIM34, TRIM38 and similar proteins

  2. XM_021925298.2 → XP_021780990.2  tripartite motif-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A096MZZ7, E5FGA9
    Conserved Domains (4) summary
    pfam05483
    Location:64 → 265
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    cd15822
    Location:290 → 493
    SPRY_PRY_TRIM5; PRY/SPRY domain in tripartite motif-binding protein 5 (TRIM5), also known as RING finger protein 88 (RNF88)
    cd16591
    Location:12 → 61
    RING-HC_TRIM5_like-C-IV; RING finger, HC subclass, found in tripartite motif-containing proteins TRIM5, TRIM6, TRIM22, TRIM34 and similar proteins
    cd19761
    Location:95 → 134
    Bbox2_TRIM5-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM5, TRIM6, TRIM22, TRIM34, TRIM38 and similar proteins

  3. XM_017948079.3 → XP_017803568.2  tripartite motif-containing protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A096MZZ7, E5FGA9
    Conserved Domains (4) summary
    pfam05483
    Location:64 → 265
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    cd15822
    Location:290 → 493
    SPRY_PRY_TRIM5; PRY/SPRY domain in tripartite motif-binding protein 5 (TRIM5), also known as RING finger protein 88 (RNF88)
    cd16591
    Location:12 → 61
    RING-HC_TRIM5_like-C-IV; RING finger, HC subclass, found in tripartite motif-containing proteins TRIM5, TRIM6, TRIM22, TRIM34 and similar proteins
    cd19761
    Location:95 → 134
    Bbox2_TRIM5-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM5, TRIM6, TRIM22, TRIM34, TRIM38 and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5D7J2.1 GenPept UniProtKB/Swiss-Prot:Q5D7J2

Gene LinkOut

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