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Gm44502 predicted readthrough transcript (NMD candidate), 44502 [ Mus musculus (house mouse) ]

Gene ID: 100134861, updated on 28-Oct-2024

Summary

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Official Symbol
Gm44502provided by MGI
Official Full Name
predicted readthrough transcript (NMD candidate), 44502provided by MGI
Primary source
MGI:MGI:3846135
See related
Ensembl:ENSMUSG00000116461 AllianceGenome:MGI:3846135
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ChkbCpt1b; Chkbcpt1b; Chkb-Cpt1b
Summary
This locus represents naturally occurring read-through transcription between the neighboring choline kinase beta (Chkb) and carnitine palmitoyltransferase 1b, muscle (Cpt1b) genes. Similar read-through transcription has also been identified between the homologous genes in human and rat. These read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to produce a protein; the functional significance of these transcripts has yet to be determined. [provided by RefSeq, Nov 2010]
Expression
Broad expression in heart adult (RPKM 118.3), testis adult (RPKM 78.3) and 21 other tissues See more
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Genomic context

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See Gm44502 in Genome Data Viewer
Location:
15 E3; 15 44.89 cM
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (89300608..89314130, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (89416405..89429927, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene kelch domain containing 7B Neighboring gene synaptonemal complex central element protein 3 Neighboring gene carnitine palmitoyltransferase 1b, muscle Neighboring gene RIKEN cDNA C730034F03 gene Neighboring gene STARR-positive B cell enhancer ABC_E7406 Neighboring gene STARR-positive B cell enhancer ABC_E9159 Neighboring gene choline kinase beta Neighboring gene mitogen-activated protein kinase 8 interacting protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The gene encoding muscle-type carnitine palmitoyltransferase I: comparison of the 5'-upstream region of human and rodent genes. Yamazaki N, et al. J Biochem, 2003 Apr. PMID 12761301
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Readthrough Gm44502

Included genes: Chkb, Cpt1b

Other Names

  • Chkb-Cpt1b readthrough transcript (NMD candidate)
  • choline kinase beta, carnitine palmitoyltransferase 1b, muscle transcription unit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_004843.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC137513, BC090627
    Related
    ENSMUST00000052315.13

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    89300608..89314130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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