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GSTA1 glutathione S-transferase alpha 1 [ Ovis aries (sheep) ]

Gene ID: 100141301, updated on 7-Feb-2024

Summary

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Gene symbol
GSTA1
Gene description
glutathione S-transferase alpha 1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
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Genomic context

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See GSTA1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 20 NC_056073.1 (24792990..24807956, complement)

Chromosome 20 - NC_056073.1Genomic Context describing neighboring genes Neighboring gene microsomal glutathione-S-transferase 1-1 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene glutathione S-transferase A1-like Neighboring gene glutathione S-transferase A1-like Neighboring gene glutathione S-transferase A4-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056073.1 Chromosome 20 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in xenobiotic metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular exosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutathione S-transferase A1
NP_001108238.1
XP_027814130.2
XP_060258961.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114766.1 → NP_001108238.1  glutathione S-transferase A1

    See identical proteins and their annotated locations for NP_001108238.1

    Status: PROVISIONAL

    Source sequence(s)
    EU399787
    UniProtKB/TrEMBL
    A0A6P3CWT7, A0A6P7D5Q5, B0LXN9
    Conserved Domains (3) summary
    PTZ00057
    Location:1 → 198
    PTZ00057; glutathione s-transferase; Provisional
    cd03208
    Location:86 → 220
    GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    cd03077
    Location:4 → 82
    GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056073.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    24792990..24807956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027958329.3 → XP_027814130.2  glutathione S-transferase A1 isoform X2

    UniProtKB/TrEMBL
    A0A6P7D5Q5
    Conserved Domains (2) summary
    cd03208
    Location:86 → 220
    GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    cd03077
    Location:4 → 82
    GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

  2. XM_060402978.1 → XP_060258961.1  glutathione S-transferase A1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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