U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Usp43 ubiquitin specific peptidase 43 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100147704, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Usp43provided by RGD
Official Full Name
ubiquitin specific peptidase 43provided by RGD
Primary source
RGD:2303824
See related
EnsemblRapid:ENSRNOG00000003785 AllianceGenome:RGD:2303824
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. Orthologous to human USP43 (ubiquitin specific peptidase 43). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 12.5), Heart (RPKM 7.2) and 8 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Usp43 in Genome Data Viewer
Location:
10q24
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (53047368..53110099, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (52549200..52611168, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (54406980..54467956, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene GSG1-like 2 Neighboring gene dehydrogenase/reductase 7C Neighboring gene uncharacterized LOC100911946 Neighboring gene cilia and flagella associated protein 52

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin carboxyl-terminal hydrolase 43
Names
ubiquitin specific protease 43
NP_001382953.1
XP_038940907.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396024.1 → NP_001382953.1  ubiquitin carboxyl-terminal hydrolase 43

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HFJ3
    Related
    ENSRNOP00000102990.1, ENSRNOT00000157747.1
    Conserved Domains (1) summary
    COG5560
    Location:77 → 706
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    53047368..53110099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084979.2 → XP_038940907.1  ubiquitin carboxyl-terminal hydrolase 43 isoform X1

    UniProtKB/TrEMBL
    A6HFJ3, D3ZED6
    Related
    ENSRNOP00000062751.2, ENSRNOT00000065383.5
    Conserved Domains (1) summary
    COG5560
    Location:77 → 711
    UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools