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PRINS psoriasis associated non-protein coding RNA induced by stress [ Homo sapiens (human) ]

Gene ID: 100169750, updated on 24-Jul-2021

Summary

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Official Symbol
PRINSprovided by HGNC
Official Full Name
psoriasis associated non-protein coding RNA induced by stressprovided by HGNC
Primary source
HGNC:HGNC:34235
Gene type
ncRNA
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NCRNA00074
Annotation information
not in current annotation release
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Genomic context

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Location:
10p12.1

Bibliography

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Related articles in PubMed

  1. Expression and functional studies on the noncoding RNA, PRINS. Szegedi K, et al. Int J Mol Sci, 2012 Dec 21. PMID 23344029, Free PMC Article
  2. Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells. Bari L, et al. Arch Dermatol Res, 2011 Dec. PMID 21750967
  3. PRINS Non-Coding RNA Regulates Nucleic Acid-Induced Innate Immune Responses of Human Keratinocytes. Danis J, et al. Front Immunol, 2017. PMID 28900430, Free PMC Article
  4. The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS. Szegedi K, et al. Exp Dermatol, 2010 Mar. PMID 20377629
  5. Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS. Sonkoly E, et al. J Biol Chem, 2005 Jun 24. PMID 15855153

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PRINS directly binds to the mRNA of IL-6 through sequence specific binding and leads to the downregulation of IL-6 at mRNA and protein level.
    Title: PRINS Non-Coding RNA Regulates Nucleic Acid-Induced Innate Immune Responses of Human Keratinocytes.
  2. PRINS may play a role in the NPM-mediated cellular stress response in the skin.
    Title: Expression and functional studies on the noncoding RNA, PRINS.
  3. silencing has no effect on LPS-induced NF-kappaB activity in normal human keratinocytes and HaCaT cells
    Title: Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells.
  4. PRINS regulates G1P3, a gene with anti-apoptotic effects in keratinocytes. siRNA-mediated inhibition of PRINS gene resulted in altered cell morphology and gene expression alterations.
    Title: The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS.
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Variation

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General gene information

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Markers

Other Names

  • psoriasis associated RNA induced by stress (non-protein coding)

NCBI Reference Sequences (RefSeq)

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Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_023388.1: Suppressed sequence

    Description
    NR_023388.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
Nucleotide Protein
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