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OPHN1 oligophrenin 1 [ Taeniopygia guttata (zebra finch) ]

Gene ID: 100228490, updated on 13-Aug-2024

Summary

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Gene symbol
OPHN1
Gene description
oligophrenin 1
See related
Ensembl:ENSTGUG00000002739
Gene type
protein coding
RefSeq status
MODEL
Organism
Taeniopygia guttata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Taeniopygia
Orthologs
human mouse all
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Genomic context

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See OPHN1 in Genome Data Viewer
Location:
chromosome: 4A
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bTaeGut1.4.pri (GCF_003957565.2) 4A NC_044216.2 (5948960..5999556)
105 previous assembly bTaeGut2.pat.W.v2 (GCF_008822105.2) 4A NC_045003.1 (5896076..5946567)

Chromosome 4A - NC_044216.2Genomic Context describing neighboring genes Neighboring gene StAR related lipid transfer domain containing 8 Neighboring gene Yip1 domain family member 6 Neighboring gene androgen receptor Neighboring gene ectodysplasin A2 receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
oligophrenin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Taeniopygia guttata Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bTaeGut1.4.pri Primary Assembly

Genomic

  1. NC_044216.2 Reference bTaeGut1.4.pri Primary Assembly

    Range
    5948960..5999556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030272484.3 → XP_030128344.3  oligophrenin-1 isoform X1

    UniProtKB/TrEMBL
    H0YX10
    Conserved Domains (4) summary
    cd07633
    Location:19 → 225
    BAR_OPHN1; The Bin/Amphiphysin/Rvs (BAR) domain of Oligophrenin-1
    PHA03307
    Location:625 → 809
    PHA03307; transcriptional regulator ICP4; Provisional
    cd04374
    Location:363 → 559
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:267 → 370
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain

  2. XM_030272485.3 → XP_030128345.3  oligophrenin-1 isoform X2

    UniProtKB/TrEMBL
    H0YX10
    Conserved Domains (3) summary
    cd07633
    Location:19 → 225
    BAR_OPHN1; The Bin/Amphiphysin/Rvs (BAR) domain of Oligophrenin-1
    cd04374
    Location:363 → 559
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:267 → 370
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain

  3. XM_030272486.3 → XP_030128346.3  oligophrenin-1 isoform X3

    UniProtKB/TrEMBL
    H0YX10
    Conserved Domains (3) summary
    cd07633
    Location:19 → 225
    BAR_OPHN1; The Bin/Amphiphysin/Rvs (BAR) domain of Oligophrenin-1
    cd04374
    Location:363 → 559
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:267 → 370
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
Nucleotide Protein
Heading Accession and Version

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