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Rrm2l1 ribonucleotide reductase regulatory subunit M2 like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100359539, updated on 2-Nov-2024

Summary

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Official Symbol
Rrm2l1provided by RGD
Official Full Name
ribonucleotide reductase regulatory subunit M2 like 1provided by RGD
Primary source
RGD:2323655
See related
EnsemblRapid:ENSRNOG00000088764 AllianceGenome:RGD:2323655
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Rrm2l1 in Genome Data Viewer
Location:
19q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (40784849..40786766, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (23879383..23881961, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (25391689..25394229)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel subunit alpha1 A Neighboring gene uncharacterized LOC134483326 Neighboring gene uncharacterized LOC120098528 Neighboring gene similar to human chromosome 19 open reading frame 53 Neighboring gene YJU2 splicing factor homolog B Neighboring gene methylthioribose-1-phosphate isomerase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in deoxyribonucleotide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ribonucleoside-diphosphate reductase subunit M2-like
Names
ribonucleotide reductase M2 polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    40784849..40786766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039098091.2 → XP_038954019.1  ribonucleoside-diphosphate reductase subunit M2-like

    Related
    ENSRNOP00000106885.1, ENSRNOT00000164809.1
    Conserved Domains (1) summary
    PLN02492
    Location:71 → 390
    PLN02492; ribonucleoside-diphosphate reductase
Nucleotide Protein Strain
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