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Ftl1l2 ferritin light chain 1 like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100359668, updated on 2-Nov-2024

Summary

Official Symbol
Ftl1l2provided by RGD
Official Full Name
ferritin light chain 1 like 2provided by RGD
Primary source
RGD:2325062
See related
EnsemblRapid:ENSRNOG00000033776 AllianceGenome:RGD:2325062
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to be involved in iron ion transport. Predicted to be located in autolysosome. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Ftl1l2 in Genome Data Viewer
Location:
6q23
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (78977712..78987254, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (73242612..73243527, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (76652033..76652975, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene Ral GTPase activating protein catalytic subunit alpha 1 Neighboring gene INSM transcriptional repressor 2 Neighboring gene high mobility group protein B1-like Neighboring gene uncharacterized LOC102546497 Neighboring gene microRNA 3593

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ferric iron binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in autolysosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ferritin light chain 1-like
Names
ferritin light chain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    78977712..78987254 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039113181.2XP_038969109.1  ferritin light chain 1-like

    UniProtKB/TrEMBL
    A0A8I6GIG4, F1M5T1
    Related
    ENSRNOP00000103057.1, ENSRNOT00000170958.1
    Conserved Domains (1) summary
    cl00264
    Location:10177
    Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins