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Hsf3 heat shock transcription factor 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100360790, updated on 2-Nov-2024

Summary

Official Symbol
Hsf3provided by RGD
Official Full Name
heat shock transcription factor 3provided by RGD
Primary source
RGD:2321468
See related
EnsemblRapid:ENSRNOG00000021694 AllianceGenome:RGD:2321468
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable chromatin DNA binding activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to heat. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 21.9), Testes (RPKM 10.6) and 8 other tissues See more
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Genomic context

See Hsf3 in Genome Data Viewer
Location:
Xq22
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (65190675..65243358, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (61181376..61233724, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (65412241..65468572, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099372 Neighboring gene microRNA 223 Neighboring gene V-set and immunoglobulin domain containing 4 Neighboring gene hephaestin Neighboring gene ubiquitin-like protein ATG12 pseudogene Neighboring gene CDGSH iron sulfur domain 3, pseudogene 1 Neighboring gene 60 kDa heat shock protein, mitochondrial pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to heat ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
heat shock factor protein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    65190675..65243358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003752067.6XP_003752115.1  heat shock factor protein 3-like

    See identical proteins and their annotated locations for XP_003752115.1

    UniProtKB/TrEMBL
    A0A8I6A0S5
    Related
    ENSRNOP00000086201.1, ENSRNOT00000041963.5
    Conserved Domains (1) summary
    smart00415
    Location:9112
    HSF; heat shock factor