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Anapc16 anaphase promoting complex subunit 16 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100360936, updated on 14-Nov-2024

Summary

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Official Symbol
Anapc16provided by RGD
Official Full Name
anaphase promoting complex subunit 16provided by RGD
Primary source
RGD:2321124
See related
EnsemblRapid:ENSRNOG00000000576 AllianceGenome:RGD:2321124
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in anaphase-promoting complex-dependent catabolic process and protein polyubiquitination. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytosol and kinetochore. Orthologous to human ANAPC16 (anaphase promoting complex subunit 16). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 93.0), Heart (RPKM 69.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Anapc16 in Genome Data Viewer
Location:
20q11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (28470282..28484601, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (27927334..27941644, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (29544626..29558928, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483913 Neighboring gene DNA-damage-inducible transcript 4 Neighboring gene activating signal cointegrator 1 complex subunit 1 Neighboring gene cytochrome c oxidase subunit 5B, pseudogene 2 Neighboring gene uncharacterized LOC134483914 Neighboring gene SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Ohta S, et al. Cell, 2010 Sep 3. PMID 20813266, Free PMC Article
  2. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins JR, et al. Science, 2010 Apr 30. PMID 20360068, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in protein K11-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein branched polyubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of anaphase-promoting complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
anaphase-promoting complex subunit 16
Names
rCG22080-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399607.1 → NP_001386536.1  anaphase-promoting complex subunit 16 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    A6K3W1

  2. NM_001399608.1 → NP_001386537.1  anaphase-promoting complex subunit 16 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    Related
    ENSRNOP00000093739.2, ENSRNOT00000119488.2

  3. NM_001399609.1 → NP_001386538.1  anaphase-promoting complex subunit 16 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    A0A8I6AKF1, A6K3W0
    Related
    ENSRNOP00000093626.1, ENSRNOT00000114556.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    28470282..28484601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278908.1 → XP_063134978.1  anaphase-promoting complex subunit 16 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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