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LOC100362384 ferritin light chain 1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 100362384, updated on 2-Nov-2024

Summary

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Symbol
LOC100362384provided by RGD
Full Name
ferritin light chain 1-likeprovided by RGD
Primary source
RGD:2318303
See related
AllianceGenome:RGD:2318303
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to be involved in iron ion transport. Predicted to be located in autolysosome. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See LOC100362384 in Genome Data Viewer
Location:
13q24
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (85649841..85650965)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (83117280..83118226)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (89253404..89254341)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene activating transcription factor 6 Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S27-like Neighboring gene DNA methyltransferase 3B, pseudogene 2 Neighboring gene dual specificity phosphatase 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ferric iron binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in autolysosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ferritin light chain 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    85649841..85650965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091410.2 → XP_038947338.1  ferritin light chain 1-like

    UniProtKB/TrEMBL
    A0A8I6GIG4
    Conserved Domains (1) summary
    cd00904
    Location:10 → 178
    Ferritin; Ferritin iron storage proteins
Nucleotide Protein Strain
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