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Ankdd1a ankyrin repeat and death domain containing 1A [ Rattus norvegicus (Norway rat) ]

Gene ID: 100362785, updated on 2-Nov-2024

Summary

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Official Symbol
Ankdd1aprovided by RGD
Official Full Name
ankyrin repeat and death domain containing 1Aprovided by RGD
Primary source
RGD:1586052
See related
EnsemblRapid:ENSRNOG00000015554 AllianceGenome:RGD:1586052
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in signal transduction. Orthologous to human ANKDD1A (ankyrin repeat and death domain containing 1A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 17.4), Brain (RPKM 9.6) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankdd1a in Genome Data Viewer
Location:
8q24
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (74912707..74938870, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (66017571..66043738, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (71034630..71057265, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene SPG21 abhydrolase domain containing, maspardin Neighboring gene pleckstrin homology domain containing O2 Neighboring gene PIF1 5'-to-3' DNA helicase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin repeat and death domain-containing protein 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    74912707..74938870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039082474.2 → XP_038938402.1  ankyrin repeat and death domain-containing protein 1A isoform X3

    UniProtKB/TrEMBL
    M0R3S6
    Related
    ENSRNOP00000063997.2, ENSRNOT00000075734.3
    Conserved Domains (3) summary
    PHA03095
    Location:21 → 335
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:181 → 212
    ANK; ANK repeat [structural motif]
    cl14633
    Location:387 → 463
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_017596076.3 → XP_017451565.1  ankyrin repeat and death domain-containing protein 1A isoform X2

    Related
    ENSRNOP00000034966.8, ENSRNOT00000033512.9

  3. XM_006243300.4 → XP_006243362.1  ankyrin repeat and death domain-containing protein 1A isoform X1

    See identical proteins and their annotated locations for XP_006243362.1

    UniProtKB/TrEMBL
    D3Z8Z7
    Conserved Domains (4) summary
    cd00204
    Location:178 → 301
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:153 → 243
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:114 → 169
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:181 → 212
    ANK; ANK repeat [structural motif]

  4. XM_039082475.2 → XP_038938403.1  ankyrin repeat and death domain-containing protein 1A isoform X4

    Conserved Domains (3) summary
    COG0666
    Location:25 → 176
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:73 → 103
    ANK; ANK repeat [structural motif]
    cl14633
    Location:245 → 321
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein Strain
Heading Accession and Version

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