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MIR3165 microRNA 3165 [ Homo sapiens (human) ]

Gene ID: 100422953, updated on 10-Oct-2023

Summary

Official Symbol
MIR3165provided by HGNC
Official Full Name
microRNA 3165provided by HGNC
Primary source
HGNC:HGNC:38335
See related
Ensembl:ENSG00000263742 miRBase:MI0014195; AllianceGenome:HGNC:38335
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mir-3165
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:
11q13.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (72072228..72072302, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (71999104..71999178, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (71783274..71783348, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene nuclear mitotic apparatus protein 1 Neighboring gene uncharacterized LOC100128494 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:71725991-71726738 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:71728895-71730094 Neighboring gene Sharpr-MPRA regulatory region 3523 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5176 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:71751839-71752624 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:71752625-71753408 Neighboring gene uncharacterized LOC124902815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:71790999-71791954 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:71791955-71792909 Neighboring gene leucine rich repeat containing 51 Neighboring gene leucine rich transmembrane and O-methyltransferase domain containing Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5180 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5181 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3713 Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036123.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP002490
    Related
    ENST00000579874.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    72072228..72072302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    71999104..71999178 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)