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MIR3654 microRNA 3654 [ Homo sapiens (human) ]

Gene ID: 100500804, updated on 17-Sep-2024

Summary

Official Symbol
MIR3654provided by HGNC
Official Full Name
microRNA 3654provided by HGNC
Primary source
HGNC:HGNC:38896
See related
Ensembl:ENSG00000284135 miRBase:MI0016054; AllianceGenome:HGNC:38896
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR3654 in Genome Data Viewer
Location:
7q33
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (133034860..133034915, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (134356394..134356449, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (132719620..132719675, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD46 Neighboring gene uncharacterized LOC100506937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:132443779-132444332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:132455865-132456366 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:132456367-132456866 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:132558086-132558347 Neighboring gene Sharpr-MPRA regulatory region 15449 Neighboring gene Sharpr-MPRA regulatory region 5703 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26679 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26680 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26681 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:132728273-132728435 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:132766583-132767217 Neighboring gene uncharacterized LOC105375512 Neighboring gene RNA, U6 small nuclear 92, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037427.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC008038
    Related
    ENST00000639535.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    133034860..133034915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    134356394..134356449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)