U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIR3678 microRNA 3678 [ Homo sapiens (human) ]

Gene ID: 100500841, updated on 10-Oct-2023

Summary

Official Symbol
MIR3678provided by HGNC
Official Full Name
microRNA 3678provided by HGNC
Primary source
HGNC:HGNC:38891
See related
Ensembl:ENSG00000264511 miRBase:MI0016079; AllianceGenome:HGNC:38891
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mir-3678
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
17q25.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (75406069..75406162)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (76298289..76298382)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (73402150..73402243)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene growth factor receptor bound protein 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12757 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:73341127-73342118 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:73343103-73343271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12759 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12760 Neighboring gene ribosomal protein L36a pseudogene 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:73346323-73346862 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:73346863-73347400 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:73348169-73348497 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr17:73376470-73377316 Neighboring gene MPRA-validated peak2996 silencer Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr17:73390107-73391015 Neighboring gene uncharacterized LOC124904060 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8965 Neighboring gene Sharpr-MPRA regulatory region 6144 Neighboring gene RNA, U6 small nuclear 938, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12763 Neighboring gene Sharpr-MPRA regulatory region 2319 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12764 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8966 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8967 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:73464760-73464928 Neighboring gene transmembrane protein 94 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8968 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:73476676-73476860 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12765 Neighboring gene microRNA 6785

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037449.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC011933
    Related
    ENST00000578455.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    75406069..75406162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    76298289..76298382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)