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Tp53 tumor protein p53 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100682525, updated on 8-Mar-2024

Summary

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Gene symbol
Tp53
Gene description
tumor protein p53
Locus tag
I79_002739
See related
Ensembl:ENSCGRG00015010036
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
P53
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613643.1 (1638391..1643801)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 7 NC_048600.1 (83421633..83433571)

NW_003613643.1Genomic Context describing neighboring genes Neighboring gene ephrin B3 Neighboring gene WD repeat containing antisense to TP53 Neighboring gene ATPase Na+/K+ transporting subunit beta 2 Neighboring gene sex hormone binding globulin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assignment of Chinese hamster p53 gene (TP53) to chromosome band 2p31, a region not involved in the karyotypic changes of a tumorigenic cell line. Vatteroni L, et al. Cytogenet Cell Genet, 1997. PMID 9284922
  2. Cloning and characterization of Chinese hamster p53 cDNA. Lee H, et al. Gene, 1997 Jan 15. PMID 9031625
  3. The p53 status of Chinese hamster V79 cells frequently used for studies on DNA damage and DNA repair. Chaung W, et al. Nucleic Acids Res, 1997 Mar 1. PMID 9023109, Free PMC Article
  4. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein tetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cellular tumor antigen p53
Names
Tumor suppressor p53
p53 tumor suppressor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243976.1 → NP_001230905.1  cellular tumor antigen p53

    See identical proteins and their annotated locations for NP_001230905.1

    Status: PROVISIONAL

    Source sequence(s)
    D86070
    UniProtKB/Swiss-Prot
    O09185, P97258, P97788, Q64397
    UniProtKB/TrEMBL
    A0A8C2QGV3
    Related
    ENSCGRP00015013122.2, ENSCGRT00015016061.2
    Conserved Domains (3) summary
    pfam00870
    Location:95 → 289
    P53; P53 DNA-binding domain
    pfam07710
    Location:319 → 357
    P53_tetramer; P53 tetramerization motif
    pfam08563
    Location:5 → 27
    P53_TAD; P53 transactivation motif

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613643.1 Reference CriGri_1.0 Primary Assembly

    Range
    1638391..1643801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048600.1 Alternate CriGri-PICRH-1.0

    Range
    83421633..83433571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O09185.1 GenPept UniProtKB/Swiss-Prot:O09185

Gene LinkOut

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