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Trappc2b trafficking protein particle complex 2B [ Rattus norvegicus (Norway rat) ]

Gene ID: 100910318, updated on 17-Aug-2024

Summary

Official Symbol
Trappc2bprovided by RGD
Official Full Name
trafficking protein particle complex 2Bprovided by RGD
Primary source
RGD:6499350
See related
EnsemblRapid:ENSRNOG00000049062 AllianceGenome:RGD:6499350
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in X-linked spondyloepiphyseal dysplasia tarda. Orthologous to human TRAPPC2 (trafficking protein particle complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 154.0), Thymus (RPKM 118.1) and 9 other tissues See more
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Genomic context

See Trappc2b in Genome Data Viewer
Location:
10q22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (36439185..36443432, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35938225..35942869, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (35036176..35040918, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095096 Neighboring gene Nedd4 binding protein 3 Neighboring gene SEC24 homolog A, COPII coat complex component Neighboring gene secretion associated, Ras related GTPase 1B Neighboring gene small nuclear ribonucleoprotein F-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
trafficking protein particle complex subunit 2B
Names
sedlin-like
trafficking protein particle complex 2
trafficking protein particle complex subunit 2
trafficking protein particle complex subunit 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271111.1NP_001258040.1  trafficking protein particle complex subunit 2B

    See identical proteins and their annotated locations for NP_001258040.1

    Status: PROVISIONAL

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    D3ZVF4
    Related
    ENSRNOP00000066171.1, ENSRNOT00000073738.4
    Conserved Domains (1) summary
    pfam04628
    Location:9136
    Sedlin_N; Sedlin, N-terminal conserved region
  2. NM_001271112.1NP_001258041.1  trafficking protein particle complex subunit 2B

    See identical proteins and their annotated locations for NP_001258041.1

    Status: PROVISIONAL

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    D3ZVF4
    Conserved Domains (1) summary
    pfam04628
    Location:9136
    Sedlin_N; Sedlin, N-terminal conserved region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    36439185..36443432 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)