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Zfp41 zinc finger protein 41 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100910508, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp41provided by RGD
Official Full Name
zinc finger protein 41provided by RGD
Primary source
RGD:1307587
See related
EnsemblRapid:ENSRNOG00000007489 AllianceGenome:RGD:1307587
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307587
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP41 (ZFP41 zinc finger protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 50.0), Spleen (RPKM 48.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp41 in Genome Data Viewer
Location:
7q34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109188010..109198546)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107307303..107320164)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (116653618..116665414)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 family member H Neighboring gene glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Neighboring gene GLI family zinc finger 4 Neighboring gene DNA topoisomerase I mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 41 homolog
Names
GLI-Kruppel family member GLI4 (oncogene HKR4)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    109188010..109198546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008765625.4 → XP_008763847.1  zinc finger protein 41 homolog

    See identical proteins and their annotated locations for XP_008763847.1

    UniProtKB/TrEMBL
    D3ZZK5
    Related
    ENSRNOP00000089045.1, ENSRNOT00000104546.2
    Conserved Domains (2) summary
    COG5189
    Location:111 → 191
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:117 → 137
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_039080529.2 → XP_038936457.1  zinc finger protein 41 homolog

    UniProtKB/TrEMBL
    D3ZZK5
    Related
    ENSRNOP00000068439.1, ENSRNOT00000076606.3
    Conserved Domains (2) summary
    COG5189
    Location:111 → 191
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:117 → 137
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_008765626.4 → XP_008763848.1  zinc finger protein 41 homolog

    See identical proteins and their annotated locations for XP_008763848.1

    UniProtKB/TrEMBL
    D3ZZK5
    Related
    ENSRNOP00000097386.1, ENSRNOT00000107500.2
    Conserved Domains (2) summary
    COG5189
    Location:111 → 191
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:117 → 137
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_063264671.1 → XP_063120741.1  zinc finger protein 41 homolog

    UniProtKB/TrEMBL
    D3ZZK5

  5. XM_039080530.2 → XP_038936458.1  zinc finger protein 41 homolog

    UniProtKB/TrEMBL
    D3ZZK5
    Related
    ENSRNOP00000099994.1, ENSRNOT00000172546.1
    Conserved Domains (2) summary
    COG5189
    Location:111 → 191
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:117 → 137
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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