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Elfn2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100910536, updated on 2-Nov-2024

Summary

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Official Symbol
Elfn2provided by RGD
Official Full Name
extracellular leucine-rich repeat and fibronectin type III domain containing 2provided by RGD
Primary source
RGD:1559693
See related
EnsemblRapid:ENSRNOG00000007934 AllianceGenome:RGD:1559693
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Elfn2-ps1; RGD1559693
Summary
Predicted to be involved in synaptic membrane adhesion. Predicted to be active in extracellular matrix; extracellular space; and postsynaptic density membrane. Orthologous to human ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See Elfn2 in Genome Data Viewer
Location:
7q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (112101998..112153280, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (110220293..110272770, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (119889786..119897038, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene cytohesin 4 Neighboring gene uncharacterized LOC134479754 Neighboring gene uncharacterized LOC102549375 Neighboring gene MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Neighboring gene caspase recruitment domain family, member 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
  2. Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Böhm D, et al. Oncol Rep, 2012 Aug. PMID 22664934, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in synaptic membrane adhesion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
extracellular leucine-rich repeat and fibronectin type III domain containing 2; protein phosphatase 1 regulatory subunit 29
Names
extracellular leucine-rich repeat and fibronectin type III containing 2
extracellular leucine-rich repeat and fibronectin type III domain containing 2, pseudogene 1
protein phosphatase 1 regulatory subunit 29-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432228.1 → NP_001419157.1  extracellular leucine-rich repeat and fibronectin type III domain containing 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    D3ZH36

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    112101998..112153280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242041.5 → XP_006242103.2  protein phosphatase 1 regulatory subunit 29

    UniProtKB/TrEMBL
    A6HSL8, D3ZH36
    Related
    ENSRNOP00000112651.1, ENSRNOT00000167735.1
    Conserved Domains (4) summary
    TIGR00864
    Location:157 → 227
    PCC; polycystin cation channel protein
    sd00031
    Location:60 → 80
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:200 → 226
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:80 → 139
    LRR_8; Leucine rich repeat

  2. XM_039080278.2 → XP_038936206.1  protein phosphatase 1 regulatory subunit 29

    Related
    ENSRNOP00000010609.3, ENSRNOT00000010609.6
    Conserved Domains (4) summary
    TIGR00864
    Location:157 → 227
    PCC; polycystin cation channel protein
    sd00031
    Location:60 → 80
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:200 → 226
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:80 → 139
    LRR_8; Leucine rich repeat

  3. XM_039080277.2 → XP_038936205.1  protein phosphatase 1 regulatory subunit 29

    UniProtKB/TrEMBL
    A6HSL8, D3ZH36
    Related
    ENSRNOP00000096572.1, ENSRNOT00000105973.2
    Conserved Domains (4) summary
    TIGR00864
    Location:157 → 227
    PCC; polycystin cation channel protein
    sd00031
    Location:60 → 80
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:200 → 226
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:80 → 139
    LRR_8; Leucine rich repeat

  4. XM_039080276.2 → XP_038936204.1  protein phosphatase 1 regulatory subunit 29

    UniProtKB/TrEMBL
    A6HSL8, D3ZH36
    Conserved Domains (4) summary
    TIGR00864
    Location:157 → 227
    PCC; polycystin cation channel protein
    sd00031
    Location:60 → 80
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:200 → 226
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:80 → 139
    LRR_8; Leucine rich repeat

  5. XM_063264450.1 → XP_063120520.1  protein phosphatase 1 regulatory subunit 29

    UniProtKB/TrEMBL
    D3ZH36
    Related
    ENSRNOP00000103739.1, ENSRNOT00000146524.1
Nucleotide Protein Strain
Heading Accession and Version

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