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Zfp182 zinc finger protein 182 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100911831, updated on 2-Nov-2024

Summary

Official Symbol
Zfp182provided by RGD
Official Full Name
zinc finger protein 182provided by RGD
Primary source
RGD:6490591
See related
EnsemblRapid:ENSRNOG00000047132 AllianceGenome:RGD:6490591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF182 (zinc finger protein 182). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 67.7), Thymus (RPKM 65.1) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp182 in Genome Data Viewer
Location:
Xq11
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (3480991..3555009)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (927439..1001474)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (908536..1000718)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 300 Neighboring gene sperm acrosome associated 5 Neighboring gene zinc finger protein 81 Neighboring gene ubiquitously-expressed, prefoldin-like chaperone Neighboring gene ETS transcription factor ELK1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401240.1NP_001388169.1  zinc finger protein 182

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
  2. NM_001401241.1NP_001388170.1  zinc finger protein 182

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    3480991..3555009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039100585.2XP_038956513.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
    Conserved Domains (3) summary
    smart00349
    Location:884
    KRAB; krueppel associated box
    COG5048
    Location:233622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:545565
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_039100575.2XP_038956503.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
    Conserved Domains (3) summary
    smart00349
    Location:884
    KRAB; krueppel associated box
    COG5048
    Location:233622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:545565
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_039100584.2XP_038956512.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
    Conserved Domains (3) summary
    smart00349
    Location:884
    KRAB; krueppel associated box
    COG5048
    Location:233622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:545565
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_063279711.1XP_063135781.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
  5. XM_063279710.1XP_063135780.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
  6. XM_039100588.2XP_038956516.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
    Related
    ENSRNOP00000085393.2, ENSRNOT00000108239.2
    Conserved Domains (3) summary
    smart00349
    Location:884
    KRAB; krueppel associated box
    COG5048
    Location:233622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:545565
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_063279709.1XP_063135779.1  zinc finger protein 182 isoform X2

    UniProtKB/TrEMBL
    M0RBY6
    Related
    ENSRNOP00000067088.3, ENSRNOT00000073016.4
  8. XM_039100573.2XP_038956501.1  zinc finger protein 182 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A273
    Conserved Domains (3) summary
    smart00349
    Location:884
    KRAB; krueppel associated box
    COG5048
    Location:233622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:545565
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_063279712.1XP_063135782.1  zinc finger protein 182 isoform X3