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Mipol1 mirror-image polydactyly 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100911970, updated on 2-Nov-2024

Summary

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Symbol
Mipol1provided by RGD
Full Name
mirror-image polydactyly 1provided by RGD
Primary source
RGD:6504372
See related
EnsemblRapid:ENSRNOG00000009151 AllianceGenome:RGD:6504372
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to be located in nucleus. Orthologous to human MIPOL1 (mirror-image polydactyly 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 20.6), Adrenal (RPKM 19.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mipol1 in Genome Data Viewer
Location:
6q23
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (80490330..80825413)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (74755293..75090403)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (78172842..78506232)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 21 Neighboring gene uncharacterized LOC120103539 Neighboring gene transfer RNA valine (anticodon AAC) 44 Neighboring gene U6 spliceosomal RNA Neighboring gene phosphoribosyl pyrophosphate synthetase 1-like 3 Neighboring gene forkhead box A1 Neighboring gene U2 spliceosomal RNA Neighboring gene tetratricopeptide repeat domain 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma. Cheung AK, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19667180, Free PMC Article
  2. A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
mirror-image polydactyly gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399384.2 → NP_001386313.1  mirror-image polydactyly gene 1 protein

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6GH45, A6HBP3
    Related
    ENSRNOP00000104410.1, ENSRNOT00000156613.1
    Conserved Domains (1) summary
    COG4372
    Location:216 → 390
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    80490330..80825413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008764677.3 → XP_008762899.1  mirror-image polydactyly gene 1 protein isoform X1

    See identical proteins and their annotated locations for XP_008762899.1

    UniProtKB/TrEMBL
    A0A8I6A2D3, F1LUS3
    Related
    ENSRNOP00000012282.8, ENSRNOT00000012282.9
    Conserved Domains (1) summary
    TIGR02168
    Location:62 → 379
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_039113186.2 → XP_038969114.1  mirror-image polydactyly gene 1 protein isoform X2

    Conserved Domains (1) summary
    COG4372
    Location:103 → 250
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

  3. XM_039113190.2 → XP_038969118.1  mirror-image polydactyly gene 1 protein isoform X3

    Conserved Domains (1) summary
    COG4372
    Location:78 → 225
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

  4. XM_039113193.2 → XP_038969121.1  mirror-image polydactyly gene 1 protein isoform X5

  5. XM_039113192.2 → XP_038969120.1  mirror-image polydactyly gene 1 protein isoform X4

    Conserved Domains (1) summary
    COG4372
    Location:66 → 213
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

  6. XM_039113194.2 → XP_038969122.1  mirror-image polydactyly gene 1 protein isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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