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LOC100912356 interferon alpha-1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 100912356, updated on 2-Nov-2024

Summary

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Symbol
LOC100912356provided by RGD
Full Name
interferon alpha-1-likeprovided by RGD
Primary source
RGD:6487214
See related
EnsemblRapid:ENSRNOG00000082845 AllianceGenome:RGD:6487214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
If1ai8; If1ai11
Summary
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Crimean-Congo hemorrhagic fever; common cold; hepatitis B; liver disease (multiple); and sarcoidosis. Orthologous to several human genes including IFNA1 (interferon alpha 1); IFNA10 (interferon alpha 10); and IFNA13 (interferon alpha 13). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See LOC100912356 in Genome Data Viewer
Location:
5q32
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (108343570..108346248, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (103227820..103230500, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (107387566..107388182, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene interferon alpha 2 like 1 Neighboring gene interferon, alpha 16-like 1 Neighboring gene interferon alpha-1-like Neighboring gene interferon alpha 2 Neighboring gene interferon alpha-1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables type I interferon receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in B cell activation involved in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in T cell activation involved in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in adaptive immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in humoral immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in natural killer cell activation involved in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to exogenous dsRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in type I interferon-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
interferon alpha-1-like
Names
interferon 1ai11
interferon 1ai8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001409402.2 → NP_001396331.1  interferon alpha-1-like precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    Related
    ENSRNOP00000111562.1, ENSRNOT00000131245.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    108343570..108346248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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