U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C5h8orf88 similar to human chromosome 8 open reading frame 88 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100912373, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
C5h8orf88provided by RGD
Official Full Name
similar to human chromosome 8 open reading frame 88provided by RGD
Primary source
RGD:6487307
See related
EnsemblRapid:ENSRNOG00000007256 AllianceGenome:RGD:6487307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to be active in cytoplasm. Orthologous to human C8orf88 (chromosome 8 open reading frame 88). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 1368.6) and Brain (RPKM 58.8) See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C5h8orf88 in Genome Data Viewer
Location:
5q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (33127385..33152914)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (28330167..28355691)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (28480029..28505430)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase 6B Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 Neighboring gene N-terminal EF-hand calcium binding protein 1 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables eukaryotic initiation factor 4E binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
similar to human chromosome 8 open reading frame 88; uncharacterized protein C8orf88 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431986.1 → NP_001418915.1  similar to human chromosome 8 open reading frame 88 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

  2. NM_001431987.1 → NP_001418916.1  similar to human chromosome 8 open reading frame 88 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A8L2Q4C3

  3. NM_001431988.1 → NP_001418917.1  similar to human chromosome 8 open reading frame 88 isoform c

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6IIA1

  4. NM_001431989.1 → NP_001418918.1  similar to human chromosome 8 open reading frame 88 isoform c

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6IIA1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    33127385..33152914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056985544.2 → XP_056841524.1  uncharacterized protein C8orf88 homolog isoform X1

    Related
    ENSRNOP00000100605.1, ENSRNOT00000139380.1

  2. XM_056985545.2 → XP_056841525.1  uncharacterized protein C8orf88 homolog isoform X2

    Related
    ENSRNOP00000102971.1, ENSRNOT00000162817.1

  3. XM_063261271.1 → XP_063117341.1  uncharacterized protein C8orf88 homolog isoform X2

  4. XM_063261270.1 → XP_063117340.1  uncharacterized protein C8orf88 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8L2Q4C3
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials