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HK1 hexokinase 1 [ Felis catus (domestic cat) ]

Gene ID: 101098403, updated on 17-Aug-2024

Summary

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Official Symbol
HK1
Official Full Name
hexokinase 1
Primary source
VGNC:VGNC:67579
See related
EnsemblRapid:ENSFCTG00005015059
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See HK1 in Genome Data Viewer
Location:
chromosome: D2
Exon count:
24
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D2 NC_058378.1 (30356873..30483521)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D2 NC_018733.3 (32378740..32517761)

Chromosome D2 - NC_058378.1Genomic Context describing neighboring genes Neighboring gene Suv3 like RNA helicase Neighboring gene hexokinase domain containing 1 Neighboring gene uncharacterized LOC123380793 Neighboring gene uncharacterized LOC109492477 Neighboring gene tachykinin receptor 2 Neighboring gene uncharacterized LOC123380794 Neighboring gene tetraspanin 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hexokinase-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058378.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    30356873..30483521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006937834.5 → XP_006937896.1  hexokinase-1 isoform X2

    UniProtKB/TrEMBL
    A0A2I2UHA4, M3W346
    Related
    ENSFCTP00005031493.1, ENSFCTT00005044202.1
    Conserved Domains (3) summary
    PTZ00107
    Location:24 → 465
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:474 → 672
    Hexokinase_1; Hexokinase
    pfam03727
    Location:678 → 912
    Hexokinase_2; Hexokinase

  2. XM_045040066.1 → XP_044896001.1  hexokinase-1 isoform X3

    UniProtKB/TrEMBL
    A0A2I2U1D6, M3W346
    Related
    ENSFCTP00005031289.1, ENSFCTT00005043937.1
    Conserved Domains (1) summary
    PTZ00107
    Location:21 → 459
    PTZ00107; hexokinase; Provisional

  3. XM_023240505.2 → XP_023096273.1  hexokinase-1 isoform X1

    UniProtKB/TrEMBL
    M3W346
    Related
    ENSFCTP00005030873.1, ENSFCTT00005043405.1
    Conserved Domains (3) summary
    PTZ00107
    Location:12 → 460
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:469 → 667
    Hexokinase_1
    pfam03727
    Location:673 → 907
    Hexokinase_2
Nucleotide Protein
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