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TRAF6 TNF receptor associated factor 6 [ Echinops telfairi (small Madagascar hedgehog) ]

Gene ID: 101658809, updated on 20-Sep-2024

Summary

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Gene symbol
TRAF6
Gene description
TNF receptor associated factor 6
Gene type
protein coding
RefSeq status
MODEL
Organism
Echinops telfairi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops
Orthologs
human mouse all
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Genomic context

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See TRAF6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
103 current ASM31398v2 (GCF_000313985.2) Unplaced Scaffold NW_022103958.1 (15111032..15134172)
101 previous assembly EchTel2.0 (GCF_000313985.1) Unplaced Scaffold NW_004558732.1 (13980351..13995042, complement)

NW_022103958.1Genomic Context describing neighboring genes Neighboring gene recombination activating 2 Neighboring gene recombination activating 1 Neighboring gene proline rich 5 like Neighboring gene ubiquitin-conjugating enzyme E2 A-like Neighboring gene COMM domain containing 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Echinops telfairi Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM31398v2 Primary Assembly

Genomic

  1. NW_022103958.1 Reference ASM31398v2 Primary Assembly

    Range
    15111032..15134172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004708302.2 → XP_004708359.1  TNF receptor-associated factor 6

    Conserved Domains (5) summary
    cd03776
    Location:370 → 519
    MATH_TRAF6; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter ...
    pfam02176
    Location:204 → 261
    zf-TRAF; TRAF-type zinc finger
    cd16643
    Location:67 → 124
    mRING-HC-C3HC3D_TRAF6; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) and similar proteins
    pfam12718
    Location:313 → 366
    Tropomyosin_1; Tropomyosin like
    pfam18048
    Location:157 → 183
    TRAF6_Z2; TNF receptor-associated factor 6 zinc finger 2
Nucleotide Protein
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