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gdnfb - glial cell derived neurotrophic factor b

Predicted to enable growth factor activity. Predicted to be involved in negative regulation of neuron apoptotic process; peripheral nervous system development; and positive regulation of branching involved in ureteric bud morphogenesis. Predicted to be active in extracellular space. Is expressed in testis. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; Parkinsonism; alcohol dependence; alcohol use disorder; and heroin dependence. Orthologous to human GDNF (glial cell derived neurotrophic factor). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa