U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIR6076 microRNA 6076 [ Homo sapiens (human) ]

Gene ID: 102464828, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Official Symbol
MIR6076provided by HGNC
Official Full Name
microRNA 6076provided by HGNC
Primary source
HGNC:HGNC:50232
See related
Ensembl:ENSG00000278038 miRBase:MI0020353; AllianceGenome:HGNC:50232
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hsa-mir-6076
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
14q21.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (49966399..49966511)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (44171585..44171697)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (50433117..50433229)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8328 Neighboring gene RNA, U6 small nuclear 189, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:50384275-50384775 Neighboring gene uncharacterized LOC100506446 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:50390203-50390704 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8329 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr14:50398632-50399133 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8330 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8331 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5713 Neighboring gene Sharpr-MPRA regulatory region 12300 Neighboring gene uncharacterized LOC105370485 Neighboring gene Sharpr-MPRA regulatory region 3168 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8333 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8332 Neighboring gene long intergenic non-protein coding RNA 1588 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:50466821-50467468 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8334 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5714 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8335 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8336 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:50469816-50470329 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:50476076-50476576 Neighboring gene long intergenic non-protein coding RNA 1599 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5716 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:50492644-50492860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5717 Neighboring gene Sharpr-MPRA regulatory region 12952 Neighboring gene Sharpr-MPRA regulatory region 10345 Neighboring gene PDZ and LIM domain 1 pseudogene 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. Voellenkle C, et al. RNA, 2012 Mar. PMID 22282338, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

Go to the top of the page Help

Other Names

  • microRNA mir-6076

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_106724.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL117692
    Related
    ENST00000617521.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    49966399..49966511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    44171585..44171697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Miscellaneous