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MIR6766 microRNA 6766 [ Homo sapiens (human) ]

Gene ID: 102466983, updated on 10-Oct-2023

Summary

Official Symbol
MIR6766provided by HGNC
Official Full Name
microRNA 6766provided by HGNC
Primary source
HGNC:HGNC:49941
See related
Ensembl:ENSG00000275101 miRBase:MI0022611; AllianceGenome:HGNC:49941
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hsa-mir-6766
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

Location:
15q26.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (89326739..89326810, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (87081562..87081633, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (89869970..89870041, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene retinaldehyde binding protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10045 Neighboring gene FA complementation group I Neighboring gene uncharacterized LOC124903548 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:89848389-89848616 Neighboring gene POLG alternative reading frame Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10046 Neighboring gene DNA polymerase gamma, catalytic subunit Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:89877323-89877824 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10047 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10048 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10049 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:89880071-89880240 Neighboring gene tRNA-Arg (anticodon TCG) 1-1 Neighboring gene POLG divergent transcript Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr15:89891730-89892929 Neighboring gene uncharacterized LOC124903549

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_106824.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC124068
    Related
    ENST00000622641.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    89326739..89326810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    87081562..87081633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)