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Zfp28 zinc finger protein 28 [ Rattus norvegicus (Norway rat) ]

Gene ID: 102548693, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp28provided by RGD
Official Full Name
zinc finger protein 28provided by RGD
Primary source
RGD:7679103
See related
EnsemblRapid:ENSRNOG00000042777 AllianceGenome:RGD:7679103
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp28l
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP28 (ZFP28 zinc finger protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 29.0), Adrenal (RPKM 28.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp28 in Genome Data Viewer
Location:
1q12
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (76522779..76539837, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (67494862..67510801, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (71167198..71183071, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 6 subfamily Z member 3 Neighboring gene olfactory receptor family 2 subfamily BD member 2 Neighboring gene small integral membrane protein 17 Neighboring gene uncharacterized LOC134482882 Neighboring gene uncharacterized LOC134482884 Neighboring gene zinc finger protein 78 Neighboring gene zinc finger protein 829 like, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 28 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427739.1 → NP_001414668.1  zinc finger protein 28 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    Related
    ENSRNOP00000103083.1, ENSRNOT00000130311.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    76522779..76539837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285400.1 → XP_063141470.1  zinc finger protein 28 homolog isoform X1

  2. XM_006228205.5 → XP_006228267.1  zinc finger protein 28 homolog isoform X2

    See identical proteins and their annotated locations for XP_006228267.1

    UniProtKB/TrEMBL
    D3ZVD4
    Related
    ENSRNOP00000020523.7, ENSRNOT00000020523.9
    Conserved Domains (6) summary
    smart00349
    Location:102 → 162
    KRAB; krueppel associated box
    COG5048
    Location:367 → 789
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:602 → 622
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:403 → 425
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:102 → 141
    KRAB; KRAB box
    pfam13465
    Location:642 → 667
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Chemical Information
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Research Materials