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Sprr2d small proline-rich protein 2D [ Rattus norvegicus (Norway rat) ]

Gene ID: 102550699, updated on 17-Aug-2024

Summary

Official Symbol
Sprr2dprovided by RGD
Official Full Name
small proline-rich protein 2Dprovided by RGD
Primary source
RGD:7559659
See related
EnsemblRapid:ENSRNOG00000009168 AllianceGenome:RGD:7559659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in keratinization. Predicted to act upstream of or within female gonad development and response to estradiol. Predicted to be located in cytoplasm and nucleus. Orthologous to human SPRR2D (small proline rich protein 2D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Uterus (RPKM 19.0) and Thymus (RPKM 4.0) See more
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Genomic context

See Sprr2d in Genome Data Viewer
Location:
2q34
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (180565685..180566282, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (177870082..177870679, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (192480676..192481990, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small proline-rich protein 2E-like Neighboring gene small proline rich protein 2B Neighboring gene small proline-rich protein 2 like 1 Neighboring gene small proline-rich protein 2D-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in female gonad development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to estradiol ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cornified envelope IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
small proline-rich protein 2D
Names
small proline-rich protein 2I-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408914.1NP_001395843.1  small proline-rich protein 2D

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    D3ZAR3
    Related
    ENSRNOP00000012135.5, ENSRNOT00000012135.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    180565685..180566282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)