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LINC01159 long intergenic non-protein coding RNA 1159 [ Homo sapiens (human) ]

Gene ID: 102682016, updated on 17-Jun-2024

Summary

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Official Symbol
LINC01159provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1159provided by HGNC
Primary source
HGNC:HGNC:49514
See related
Ensembl:ENSG00000229743 MIM:618208; AllianceGenome:HGNC:49514
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
linc-Brn1b
Summary
Predicted to act upstream of or within cerebellar cortex structural organization; homeostasis of number of cells within a tissue; and regulation of gene expression. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward kidney (RPKM 2.1) See more
Orthologs
mouse all
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Genomic context

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See LINC01159 in Genome Data Viewer
Location:
2q12.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (104865497..104872595, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (105326681..105333779, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (105481955..105489053, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene POU3F3 adjacent non-coding transcript 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:105460844-105461368 Neighboring gene VISTA enhancer hs1553 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11835 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:105470177-105470766 Neighboring gene uncharacterized LOC124908045 Neighboring gene Sharpr-MPRA regulatory region 193 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:105488734-105489459 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11836 Neighboring gene POU class 3 homeobox 3 Neighboring gene VISTA enhancer hs990 Neighboring gene MRPS9 antisense RNA 2 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:105585853-105587052 Neighboring gene Sharpr-MPRA regulatory region 1600 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:105621477-105622097 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16309 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16310 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16311 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:105654567-105655509 Neighboring gene mitochondrial ribosomal protein S9 Neighboring gene VISTA enhancer hs868 Neighboring gene uncharacterized LOC105373527 Neighboring gene MRPS9 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Sauvageau M, et al. Elife, 2013 Dec 31. PMID 24381249, Free PMC Article
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Homology

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110373.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC018730
    Related
    ENST00000433433.1

  2. NR_110374.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3' exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC018730

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    104865497..104872595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    105326681..105333779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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