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ITGAV integrin subunit alpha V [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105098976, updated on 10-Oct-2024

Summary

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Gene symbol
ITGAV
Gene description
integrin subunit alpha V
Locus tag
Cadr_000007082
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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See ITGAV in Genome Data Viewer
Location:
chromosome: 4
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 4 NC_087439.1 (57611219..57700809)
101 previous assembly CamDro3 (GCF_000803125.2) 5 NC_044515.1 (56052047..56129777)

Chromosome 4 - NC_087439.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135321148 Neighboring gene trans-1,2-dihydrobenzene-1,2-diol dehydrogenase-like Neighboring gene uncharacterized LOC116153067 Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene tRNA selenocysteine 1-associated protein 1-like Neighboring gene family with sequence similarity 171 member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning and phylogenetic analysis of integrins alphavbeta1 and alphavbeta6 of one-humped camel (Camelus dromedarius). Du J, et al. Vet Immunol Immunopathol, 2010 May 15. PMID 20015555
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-V
Names
integrin alpha V

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001303572.1 → NP_001290501.1  integrin alpha-V precursor

    See identical proteins and their annotated locations for NP_001290501.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ914571
    UniProtKB/TrEMBL
    A0A5N4E7R7, D2SYX8
    Conserved Domains (4) summary
    smart00191
    Location:367 → 421
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:467 → 914
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:221 → 271
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
    sd00039
    Location:51 → 120
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087439.1 Reference mCamDro1.pat

    Range
    57611219..57700809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064484635.1 → XP_064340705.1  integrin alpha-V isoform X2

  2. XM_010991746.3 → XP_010990048.1  integrin alpha-V isoform X1

    UniProtKB/TrEMBL
    A0A5N4E7R7
    Conserved Domains (4) summary
    smart00191
    Location:366 → 420
    Int_alpha; Integrin alpha (beta-propellor repeats)
    sd00039
    Location:51 → 119
    7WD40; WD40 repeat [structural motif]
    pfam08441
    Location:466 → 913
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:220 → 270
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

  3. XM_031451101.2 → XP_031306961.1  integrin alpha-V isoform X2

    UniProtKB/TrEMBL
    A0A5N4E7R7
    Conserved Domains (4) summary
    smart00191
    Location:304 → 358
    Int_alpha; Integrin alpha (beta-propellor repeats)
    sd00039
    Location:63 → 120
    7WD40; WD40 repeat [structural motif]
    pfam08441
    Location:404 → 851
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:158 → 208
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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