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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_033006.2 RefSeqGene
- Range
-
5090..31929
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001271888.2 → NP_001258817.1 calcium and integrin-binding family member 2 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate exon, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC090260
- Consensus CDS
-
CCDS61722.1
- UniProtKB/Swiss-Prot
-
O75838
- Related
- ENSP00000442459.1, ENST00000539011.5
- Conserved Domains (1) summary
-
- COG5126
Location:25 → 135
- FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
-
NM_001271889.2 → NP_001258818.1 calcium and integrin-binding family member 2 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks two alternate exons resulting in the loss of an in-frame segment in the 5' coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AC090260
- Consensus CDS
-
CCDS61723.1
- UniProtKB/Swiss-Prot
-
O75838
- Related
- ENSP00000453488.1, ENST00000557846.5
- Conserved Domains (1) summary
-
- COG5126
Location:19 → 129
- FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
-
NM_001301224.2 → NP_001288153.1 calcium and integrin-binding family member 2 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate exon and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (4) is longer than isoform 1.
- Source sequence(s)
-
AC090260
- UniProtKB/Swiss-Prot
-
O75838
- Conserved Domains (1) summary
-
- cl25352
Location:69 → 183
- EFh_PEF; The penta-EF hand (PEF) family
-
NM_006383.4 → NP_006374.1 calcium and integrin-binding family member 2 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1.
- Source sequence(s)
-
AC090260
- Consensus CDS
-
CCDS10296.1
- UniProtKB/Swiss-Prot
- B4DDF0, H0YM71, O75838, Q05BT6
- UniProtKB/TrEMBL
-
Q5TZX7
- Related
- ENSP00000258930.3, ENST00000258930.8
- Conserved Domains (1) summary
-
- COG5126
Location:68 → 178
- FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
RNA
-
NR_125435.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC090260
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000015.10 Reference GRCh38.p14 Primary Assembly
- Range
-
78104606..78131535 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005254126.4 → XP_005254183.1 calcium and integrin-binding family member 2 isoform X1
- UniProtKB/TrEMBL
-
Q5TZX7
- Conserved Domains (2) summary
-
- cd00051
Location:107 → 174
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam13499
Location:111 → 173
- EF-hand_7; EF-hand domain pair
-
XM_011521161.2 → XP_011519463.1 calcium and integrin-binding family member 2 isoform X3
- UniProtKB/TrEMBL
-
H0YKC8
- Related
- ENSP00000452752.1, ENST00000560618.5
- Conserved Domains (2) summary
-
- cd00051
Location:64 → 131
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam13499
Location:68 → 130
- EF-hand_7; EF-hand domain pair
-
XM_047432110.1 → XP_047288066.1 calcium and integrin-binding family member 2 isoform X2
Alternate T2T-CHM13v2.0
Genomic
-
NC_060939.1 Alternate T2T-CHM13v2.0
- Range
-
75967162..75994101 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054377207.1 → XP_054233182.1 calcium and integrin-binding family member 2 isoform X1
- UniProtKB/TrEMBL
-
Q5TZX7
-
XM_054377209.1 → XP_054233184.1 calcium and integrin-binding family member 2 isoform X3
- UniProtKB/TrEMBL
-
H0YKC8
-
XM_054377208.1 → XP_054233183.1 calcium and integrin-binding family member 2 isoform X2