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LIMASI lncRNA inflammatory and mucous response associated, antisense to ICAM1 [ Homo sapiens (human) ]

Gene ID: 105372272, updated on 28-Oct-2024

Summary

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Official Symbol
LIMASIprovided by HGNC
Official Full Name
lncRNA inflammatory and mucous response associated, antisense to ICAM1provided by HGNC
Primary source
HGNC:HGNC:56357
See related
AllianceGenome:HGNC:56357
Gene type
ncRNA
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LASI
Expression
Low expression observed in reference dataset See more
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Genomic context

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See LIMASI in Genome Data Viewer
Location:
19p13.2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (10260010..10283450, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (10386213..10409560, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 10 pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:10330242-10330742 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:10330743-10331243 Neighboring gene sphingosine-1-phosphate receptor 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13944 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10340651-10341365 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10059 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13946 Neighboring gene microRNA 4322 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13947 Neighboring gene Sharpr-MPRA regulatory region 3154 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13948 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10060 Neighboring gene H3K27ac hESC enhancers GRCh37_chr19:10362245-10362818 and GRCh37_chr19:10362819-10363392 Neighboring gene mitochondrial ribosomal protein L4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13951 Neighboring gene Sharpr-MPRA regulatory region 14536 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13952 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13953 Neighboring gene intercellular adhesion molecule 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13954 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10397303-10398272 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10061 Neighboring gene ICAM4 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10062 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10402483-10403475 Neighboring gene intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) Neighboring gene intercellular adhesion molecule 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype. Devadoss D, et al. iScience, 2022 Aug 19. PMID 35789750, Free PMC Article
  2. Increased Expression of LASI lncRNA Regulates the Cigarette Smoke and COPD Associated Airway Inflammation and Mucous Cell Hyperplasia. Manevski M, et al. Front Immunol, 2022. PMID 35774797, Free PMC Article
  3. A long noncoding RNA antisense to ICAM-1 is involved in allergic asthma associated hyperreactive response of airway epithelial cells. Devadoss D, et al. Mucosal Immunol, 2021 May. PMID 33122732, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

Genotypes

General gene information

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Other Names

  • CTD-2369P2.5
  • lncRNA on the antisense strand of ICAM-1

Clone Names

  • AC011511.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    10260010..10283450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_007067138.1 RNA Sequence

  2. XR_007067137.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    10386213..10409560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_007088898.1 RNA Sequence

  2. XR_007088897.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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