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LNCPOIR lncRNA periodontal mesenchymal stem cell osteogenesis related [ Homo sapiens (human) ]

Gene ID: 105377959, updated on 10-Oct-2023

Summary

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Official Symbol
LNCPOIRprovided by HGNC
Official Full Name
lncRNA periodontal mesenchymal stem cell osteogenesis relatedprovided by HGNC
Primary source
HGNC:HGNC:54521
See related
Ensembl:ENSG00000226079
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
POIR; lncRNA-POIR
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
6q22.1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (114476925..114545320, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (115660088..115728482, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene HDAC2 and HS3ST5 antisense RNA 2 Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 5 Neighboring gene RNA, 5S ribosomal pseudogene 213 Neighboring gene NANOG hESC enhancer GRCh37_chr6:114603304-114603805 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:114640738-114641477 Neighboring gene uncharacterized LOC107986638 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr6:114683371-114683962 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:114683963-114684552 Neighboring gene Sharpr-MPRA regulatory region 3090 Neighboring gene DnaJ heat shock protein family (Hsp40) member A1 pseudogene 4 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:114742086-114742751 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:114743417-114744081 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:114745558-114746227 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:114746228-114746898 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:114746899-114747567 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:114747568-114748238 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:114748909-114749578 Neighboring gene NANOG hESC enhancer GRCh37_chr6:114885549-114886071 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:115046932-115047452 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:115047453-115047971 Neighboring gene RNA, U6 small nuclear 475, pseudogene Neighboring gene uncharacterized LOC107986639 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24974 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:115322458-115323657

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of periodontitis patients. Wang L, et al. Cell Death Dis, 2016 Aug 11. PMID 27512949, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. miR-182 overexpression in the inflammatory microenvironment resulted in an imbalance in the lncRNA-POIR-miR-182 regulatory network.
    Title: Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of periodontitis patients.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

Genotypes

General gene information

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Other Names

  • periodontal mesenchymal stem cell osteogenesis impairment related lncRNA

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_183487.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL138830

  2. NR_183488.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL138830
    Related
    ENST00000435802.2

  3. NR_183489.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL138830
    Related
    ENST00000652989.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    114476925..114545320 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    115660088..115728482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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