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Dock9 dedicator of cytokinesis 9 [ Mus musculus (house mouse) ]

Gene ID: 105445, updated on 2-Nov-2024

Summary

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Official Symbol
Dock9provided by MGI
Official Full Name
dedicator of cytokinesis 9provided by MGI
Primary source
MGI:MGI:106321
See related
Ensembl:ENSMUSG00000025558 AllianceGenome:MGI:106321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zizimin1; D14Wsu89e; mKIAA1058; B230309H04Rik
Summary
Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in positive regulation of GTPase activity. Predicted to be located in endomembrane system and membrane. Is expressed in extraembryonic component; forelimb bud; forelimb bud mesenchyme; and neocortex. Orthologous to human DOCK9 (dedicator of cytokinesis 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in cerebellum adult (RPKM 15.8), lung adult (RPKM 13.0) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Dock9 in Genome Data Viewer
Location:
14 E5; 14 65.28 cM
Exon count:
63
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (121772026..122038465, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (121538365..121797900, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 15 (oligopeptide transporter), member 1 Neighboring gene STARR-seq mESC enhancer starr_37731 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7355 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122197085-122197385 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122197667-122197968 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122223986-122224286 Neighboring gene STARR-seq mESC enhancer starr_37739 Neighboring gene RIKEN cDNA 1810041H14 gene Neighboring gene STARR-positive B cell enhancer ABC_E10843 Neighboring gene predicted gene 9395 Neighboring gene STARR-positive B cell enhancer ABC_E9906 Neighboring gene STARR-positive B cell enhancer mm9_chr14:122277628-122277929 Neighboring gene ubiquitin associated domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma. Dai W, et al. Cell Death Dis, 2020 Sep 11. PMID 32917852, Free PMC Article
  2. Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons. Kuramoto K, et al. J Neurosci Res, 2009 Jun. PMID 19156867
  3. Roles of the DOCK-D family proteins in a mouse model of neuroinflammation. Namekata K, et al. J Biol Chem, 2020 May 8. PMID 32241915, Free PMC Article
  4. Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. Nishikimi A, et al. FEBS Lett, 2005 Feb 14. PMID 15710388
  5. The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Jaudon F, et al. Mol Biol Cell, 2015 Jun 1. PMID 25851601, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/beta-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma.
    Title: Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/β-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma.
  2. Thus, these results suggest that Zizimin1 plays an important role in dendrite growth in hippocampal neurons through activation of Cdc42.
    Title: Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (1)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables small GTPase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dedicator of cytokinesis protein 9
Names
cdc42 guanine nucleotide exchange factor zizimin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081039.1 → NP_001074508.1  dedicator of cytokinesis protein 9 isoform 1

    See identical proteins and their annotated locations for NP_001074508.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC126253, AC165272
    Consensus CDS
    CCDS37018.1
    UniProtKB/TrEMBL
    B2RXS7, F8VPN7
    Related
    ENSMUSP00000047881.8, ENSMUST00000040700.9
    Conserved Domains (5) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1629 → 2069
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam00169
    Location:172 → 277
    PH; PH domain
    pfam11878
    Location:60 → 151
    DUF3398; Domain of unknown function (DUF3398)

  2. NM_001128307.1 → NP_001121779.1  dedicator of cytokinesis protein 9 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 3 which is shorter and has distinct N- and C-termini, compared to isoform 1.
    Source sequence(s)
    AC126253, AC165272
    Consensus CDS
    CCDS88728.1
    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    UniProtKB/TrEMBL
    A0A5F8MPL9
    Related
    ENSMUSP00000159030.2, ENSMUST00000239077.2
    Conserved Domains (5) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1621 → 2049
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam00169
    Location:186 → 291
    PH; PH domain
    pfam11878
    Location:74 → 165
    DUF3398; Domain of unknown function (DUF3398)

  3. NM_001128308.1 → NP_001121780.1  dedicator of cytokinesis protein 9 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 4 which is shorter and has distinct N- and C-termini, compared to isoform 1.
    Source sequence(s)
    AC126253, AC165272
    Consensus CDS
    CCDS84162.1
    UniProtKB/TrEMBL
    A0A1D5RLE0, B2RY08
    Related
    ENSMUSP00000148328.2, ENSMUST00000212376.3
    Conserved Domains (5) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1620 → 2036
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam00169
    Location:186 → 291
    PH; PH domain
    pfam11878
    Location:74 → 165
    DUF3398; Domain of unknown function (DUF3398)

  4. NM_001347596.1 → NP_001334525.1  dedicator of cytokinesis protein 9 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC126253, AC165272, BG076874, BI134428, BM949694, BQ179803, CA557924, CB722727, CF173273, CF532607, CF533751, CF537691, CF539660, CF723234, CK625091, CK637241, CN706706
    Consensus CDS
    CCDS84161.1
    UniProtKB/TrEMBL
    A0A1D5RMM1, B2RXS7
    Related
    ENSMUSP00000148834.2, ENSMUST00000212181.2

  5. NM_134074.2 → NP_598835.2  dedicator of cytokinesis protein 9 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences in the coding region, including an alternate exon in the 5' coding region, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC126253, AC165155, AC165272
    Consensus CDS
    CCDS49569.1
    UniProtKB/TrEMBL
    B2RY79, E9QMR2
    Related
    ENSMUSP00000097872.4, ENSMUST00000100299.11
    Conserved Domains (5) summary
    cd08697
    Location:636 → 825
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1600 → 2014
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:169 → 292
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam00169
    Location:174 → 279
    PH; PH domain
    pfam11878
    Location:62 → 153
    DUF3398; Domain of unknown function (DUF3398)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    121772026..122038465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158355.1 → XP_036014248.1  dedicator of cytokinesis protein 9 isoform X8

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2098
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  2. XM_011244881.4 → XP_011243183.1  dedicator of cytokinesis protein 9 isoform X4

    UniProtKB/TrEMBL
    B2RY79
    Conserved Domains (4) summary
    cd08697
    Location:636 → 825
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1632 → 2086
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:169 → 292
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:45 → 155
    DUF3398; Domain of unknown function (DUF3398)

  3. XM_017315759.3 → XP_017171248.1  dedicator of cytokinesis protein 9 isoform X24

    UniProtKB/TrEMBL
    B2RY79
    Conserved Domains (4) summary
    cd08697
    Location:636 → 825
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1609 → 2037
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:169 → 292
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:45 → 155
    DUF3398; Domain of unknown function (DUF3398)

  4. XM_017315757.3 → XP_017171246.1  dedicator of cytokinesis protein 9 isoform X14

    UniProtKB/TrEMBL
    B2RY79
    Conserved Domains (4) summary
    cd08697
    Location:636 → 825
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1609 → 2063
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:169 → 292
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:45 → 155
    DUF3398; Domain of unknown function (DUF3398)

  5. XM_006518358.5 → XP_006518421.1  dedicator of cytokinesis protein 9 isoform X20

    UniProtKB/TrEMBL
    B2RY79
    Conserved Domains (4) summary
    cd08697
    Location:636 → 825
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1632 → 2046
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:169 → 292
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:45 → 155
    DUF3398; Domain of unknown function (DUF3398)

  6. XM_036158360.1 → XP_036014253.1  dedicator of cytokinesis protein 9 isoform X27

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1612 → 2026
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  7. XM_036158357.1 → XP_036014250.1  dedicator of cytokinesis protein 9 isoform X21

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1620 → 2046
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  8. XM_006518357.5 → XP_006518420.1  dedicator of cytokinesis protein 9 isoform X18

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1620 → 2048
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  9. XM_006518350.5 → XP_006518413.1  dedicator of cytokinesis protein 9 isoform X10

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1620 → 2074
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  10. XM_006518348.5 → XP_006518411.1  dedicator of cytokinesis protein 9 isoform X7

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1643 → 2083
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  11. XM_006518345.5 → XP_006518408.1  dedicator of cytokinesis protein 9 isoform X2

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1643 → 2097
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  12. XM_030247579.2 → XP_030103439.1  dedicator of cytokinesis protein 9 isoform X26

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1613 → 2027
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  13. XM_030247578.2 → XP_030103438.1  dedicator of cytokinesis protein 9 isoform X23

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1613 → 2039
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  14. XM_036158358.1 → XP_036014251.1  dedicator of cytokinesis protein 9 isoform X22

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1613 → 2041
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  15. XM_006518352.5 → XP_006518415.1  dedicator of cytokinesis protein 9 isoform X13

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1613 → 2067
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  16. XM_036158359.1 → XP_036014252.1  dedicator of cytokinesis protein 9 isoform X25

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1621 → 2035
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  17. XM_017315758.3 → XP_017171247.1  dedicator of cytokinesis protein 9 isoform X19

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1621 → 2047
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  18. XM_006518356.5 → XP_006518419.1  dedicator of cytokinesis protein 9 isoform X17

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1621 → 2049
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  19. XM_006518349.5 → XP_006518412.1  dedicator of cytokinesis protein 9 isoform X9

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1621 → 2075
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  20. XM_006518355.5 → XP_006518418.1  dedicator of cytokinesis protein 9 isoform X16

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2058
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  21. XM_017315756.3 → XP_017171245.1  dedicator of cytokinesis protein 9 isoform X12

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2070
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  22. XM_006518351.5 → XP_006518414.1  dedicator of cytokinesis protein 9 isoform X11

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2072
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  23. XM_006518347.5 → XP_006518410.1  dedicator of cytokinesis protein 9 isoform X6

    UniProtKB/TrEMBL
    B2RY08
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2084
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  24. XM_006518346.5 → XP_006518409.1  dedicator of cytokinesis protein 9 isoform X3

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2096
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  25. XM_006518344.5 → XP_006518407.1  dedicator of cytokinesis protein 9 isoform X1

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2098
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  26. XM_006518354.5 → XP_006518417.1  dedicator of cytokinesis protein 9 isoform X15

    UniProtKB/Swiss-Prot
    Q8BIK4, Q921Y6
    Conserved Domains (4) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1644 → 2098
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  27. XM_030247584.1 → XP_030103444.1  dedicator of cytokinesis protein 9 isoform X28

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1599 → 2013
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  28. XM_030247583.1 → XP_030103443.1  dedicator of cytokinesis protein 9 isoform X36

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1599 → 2025
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  29. XM_017315765.1 → XP_017171254.1  dedicator of cytokinesis protein 9 isoform X37

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1607 → 2061
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  30. XM_030247582.1 → XP_030103442.1  dedicator of cytokinesis protein 9 isoform X35

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1630 → 2056
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  31. XM_030247581.1 → XP_030103441.1  dedicator of cytokinesis protein 9 isoform X34

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1630 → 2070
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  32. XM_030247580.1 → XP_030103440.1  dedicator of cytokinesis protein 9 isoform X33

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1630 → 2082
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  33. XM_017315755.1 → XP_017171244.1  dedicator of cytokinesis protein 9 isoform X5

    UniProtKB/TrEMBL
    B2RXS7
    Conserved Domains (4) summary
    cd08697
    Location:634 → 823
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11698
    Location:1630 → 2084
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9
    cd13267
    Location:167 → 290
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:43 → 153
    DUF3398; Domain of unknown function (DUF3398)

  34. XM_036158362.1 → XP_036014255.1  dedicator of cytokinesis protein 9 isoform X32

    Conserved Domains (1) summary
    cd11698
    Location:672 → 1100
    DHR2_DOCK9; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 9

  35. XM_006518362.5 → XP_006518425.1  dedicator of cytokinesis protein 9 isoform X30

    Conserved Domains (3) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  36. XM_006518361.5 → XP_006518424.1  dedicator of cytokinesis protein 9 isoform X29

    Conserved Domains (3) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

  37. XM_036158361.1 → XP_036014254.1  dedicator of cytokinesis protein 9 isoform X31

    Conserved Domains (3) summary
    cd08697
    Location:648 → 837
    C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd13267
    Location:181 → 304
    PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
    pfam11878
    Location:57 → 167
    DUF3398; Domain of unknown function (DUF3398)

RNA

  1. XR_874271.4 RNA Sequence

  2. XR_383125.5 RNA Sequence

  3. XR_874272.4 RNA Sequence

  4. XR_004938359.1 RNA Sequence

  5. XR_874275.4 RNA Sequence

  6. XR_383126.5 RNA Sequence

  7. XR_383127.5 RNA Sequence

  8. XR_003950813.2 RNA Sequence

  9. XR_003950810.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BIK4.2 GenPept UniProtKB/Swiss-Prot:Q8BIK4

Gene LinkOut

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