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SREBF2 sterol regulatory element binding transcription factor 2 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105858553, updated on 13-Mar-2024

Summary

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Gene symbol
SREBF2
Gene description
sterol regulatory element binding transcription factor 2
See related
Ensembl:ENSMICG00000000913
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See SREBF2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 7 NC_033666.1 (5358585..5429302)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012200130.1 (1139680..1210402, complement)

Chromosome 7 - NC_033666.1Genomic Context describing neighboring genes Neighboring gene meiotic double-stranded break formation protein 1 Neighboring gene 3'-5' exoribonuclease 1 pseudogene Neighboring gene coiled-coil domain containing 134 Neighboring gene uncharacterized LOC105858558 Neighboring gene shisa family member 8 Neighboring gene TNF receptor superfamily member 13C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of cholesterol storage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol regulatory element-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033666.1 Reference Mmur_3.0 Primary Assembly

    Range
    5358585..5429302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012741773.2 → XP_012597227.1  sterol regulatory element-binding protein 2

    UniProtKB/TrEMBL
    A0A8C5VVV9
    Related
    ENSMICP00000028206.2, ENSMICT00000036188.2
    Conserved Domains (1) summary
    pfam00010
    Location:328 → 378
    HLH; Helix-loop-helix DNA-binding domain
Nucleotide Protein
Heading Accession and Version

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