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Sft2d1 SFT2 domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 106489, updated on 2-Nov-2024

Summary

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Official Symbol
Sft2d1provided by MGI
Official Full Name
SFT2 domain containing 1provided by MGI
Primary source
MGI:MGI:1918689
See related
Ensembl:ENSMUSG00000073468 AllianceGenome:MGI:1918689
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5630401J11Rik
Summary
Predicted to be involved in protein transport and vesicle-mediated transport. Predicted to be located in several cellular components, including cytoplasm; endomembrane system; and intracellular membrane-bounded organelle. Orthologous to human SFT2D1 (SFT2 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in duodenum adult (RPKM 38.0), CNS E18 (RPKM 33.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Sft2d1 in Genome Data Viewer
Location:
17 A1; 17 4.92 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (8529920..8546274)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (8311088..8327442)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33799 Neighboring gene predicted gene 8465 Neighboring gene STARR-positive B cell enhancer ABC_E1188 Neighboring gene RIKEN cDNA 4930506C21 gene Neighboring gene mitochondrial pyruvate carrier 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8503785-8503968 Neighboring gene proline rich 18 Neighboring gene predicted gene, 46592 Neighboring gene protein FAM32A pseudogene Neighboring gene brachyury 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC102361

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vesicle transport protein SFT2A
Names
SFT2 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357890.1 → NP_001344819.1  vesicle transport protein SFT2A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC164431, AW049769
    Conserved Domains (1) summary
    pfam04178
    Location:1 → 95
    Got1; Got1/Sft2-like family

  2. NM_134114.2 → NP_598875.2  vesicle transport protein SFT2A isoform 1

    See identical proteins and their annotated locations for NP_598875.2

    Status: VALIDATED

    Source sequence(s)
    AK151338, CAAA01222630
    Consensus CDS
    CCDS49945.1
    UniProtKB/Swiss-Prot
    A1L3Q4, Q5SSN7
    Related
    ENSMUSP00000117294.2, ENSMUST00000154553.2
    Conserved Domains (1) summary
    pfam04178
    Location:38 → 155
    Got1; Got1/Sft2-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    8529920..8546274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246185.4 → XP_011244487.1  vesicle transport protein SFT2A isoform X1

    See identical proteins and their annotated locations for XP_011244487.1

    Conserved Domains (1) summary
    pfam04178
    Location:1 → 95
    Got1; Got1/Sft2-like family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SSN7.1 GenPept UniProtKB/Swiss-Prot:Q5SSN7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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