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Ldhal6b lactate dehydrogenase A-like 6B [ Mus musculus (house mouse) ]

Gene ID: 106557, updated on 28-Oct-2024

Summary

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Official Symbol
Ldhal6bprovided by MGI
Official Full Name
lactate dehydrogenase A-like 6Bprovided by MGI
Primary source
MGI:MGI:2146830
See related
Ensembl:ENSMUSG00000101959 AllianceGenome:MGI:2146830
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LDHL; Ldhal; 4933402O15Rik
Summary
Predicted to enable L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate metabolic process. Located in mitochondrion. Orthologous to several human genes including LDHAL6B (lactate dehydrogenase A like 6B). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human all
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Genomic context

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See Ldhal6b in Genome Data Viewer
Location:
17 A1; 17 3.17 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (5467598..5469042, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (5417323..5418767, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene AT-rich interaction domain 1B Neighboring gene STARR-seq mESC enhancer starr_41683 Neighboring gene tubulin, alpha 1B pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10929 Neighboring gene STARR-seq mESC enhancer starr_41685 Neighboring gene predicted gene, 34854 Neighboring gene STARR-seq mESC enhancer starr_41691 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:5295725-5295926 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:5296016-5296125 Neighboring gene STARR-positive B cell enhancer mm9_chr17:5303477-5303778 Neighboring gene STARR-positive B cell enhancer mm9_chr17:5429429-5429729 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:5440198-5440381 Neighboring gene transmembrane protein 242 Neighboring gene predicted gene 29050 Neighboring gene STARR-positive B cell enhancer ABC_E3179 Neighboring gene predicted gene, 52310 Neighboring gene non-SMC condensin II complex, subunit H2 pseudogene Neighboring gene zinc finger, DHHC domain containing 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice. Oyama Y, et al. Asian J Androl, 2022 May-Jun. PMID 34290169, Free PMC Article
  2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-lactate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-lactate dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in lactate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyruvate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
L-lactate dehydrogenase A-like 6B
NP_780558.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175349.2 → NP_780558.1  L-lactate dehydrogenase A-like 6B

    See identical proteins and their annotated locations for NP_780558.1

    Status: PROVISIONAL

    Source sequence(s)
    AY280363
    Consensus CDS
    CCDS79501.1
    UniProtKB/TrEMBL
    Q8BVP2
    Related
    ENSMUSP00000139572.2, ENSMUST00000189788.2
    Conserved Domains (2) summary
    cd05293
    Location:70 → 379
    LDH_1; A subgroup of L-lactate dehydrogenases
    TIGR01771
    Location:75 → 375
    L-LDH-NAD; L-lactate dehydrogenase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    5467598..5469042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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