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CELF2 CUGBP Elav-like family member 2 [ Homo sapiens (human) ]

Gene ID: 10659, updated on 3-Apr-2024

Summary

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Official Symbol
CELF2provided by HGNC
Official Full Name
CUGBP Elav-like family member 2provided by HGNC
Primary source
HGNC:HGNC:2550
See related
Ensembl:ENSG00000048740 MIM:602538; AllianceGenome:HGNC:2550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ETR3; DEE97; ETR-3; NAPOR; CELF-2; CUGBP2; BRUNOL3; CUG-BP2
Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Expression
Broad expression in brain (RPKM 19.5), bone marrow (RPKM 16.3) and 21 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
10p14
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (10462550..11336675)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (10472957..11348760)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (10504513..11378674)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984207 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:10409107-10409607 Neighboring gene CELF2 divergent transript Neighboring gene NANOG hESC enhancer GRCh37_chr10:10570129-10570630 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2120 Neighboring gene NANOG hESC enhancer GRCh37_chr10:10631025-10631575 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2991 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:10693065-10693682 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2992 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2121 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:10738713-10739255 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:10809675-10809828 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:10839838-10840532 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:10840533-10841226 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:10846798-10847997 Neighboring gene NANOG hESC enhancer GRCh37_chr10:10862511-10863057 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:10872688-10873887 Neighboring gene ORMDL1 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2122 Neighboring gene surfactant associated 1, lncRNA Neighboring gene long intergenic non-protein coding RNA 710 Neighboring gene uncharacterized LOC124902376 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2123 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2124 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:11075383-11075893 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:11091414-11091914 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:11113336-11114535 Neighboring gene CELF2 antisense RNA 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2125 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2126 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2993 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2994 Neighboring gene Sharpr-MPRA regulatory region 12202 Neighboring gene Sharpr-MPRA regulatory region 4729 Neighboring gene NANOG hESC enhancer GRCh37_chr10:11224724-11225225 Neighboring gene uncharacterized LOC124902375 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2995 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2996 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2997 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2999 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3000 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3001 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3002 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3003 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3005 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3007 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3008 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:11334439-11334940 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3009 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:11334941-11335440 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:11357313-11357819 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:11357820-11358325 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3010 Neighboring gene uncharacterized LOC105376409 Neighboring gene CELF2 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2127 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3011 Neighboring gene NANOG hESC enhancer GRCh37_chr10:11482790-11483302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:11485575-11486237 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:11486238-11486901 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3012 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3013 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:11493719-11494219 Neighboring gene uncharacterized LOC105376411 Neighboring gene USP6 N-terminal like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy. Itai T, et al. Hum Mutat, 2021 Jan. PMID 33131106
  2. RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery. Chatrikhi R, et al. Cell Rep, 2019 Sep 10. PMID 31509743, Free PMC Article
  3. Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer. Piqué L, et al. Oncogene, 2019 Nov. PMID 31409895
  4. Pleotropic role of RNA binding protein CELF2 in autophagy induction. New J, et al. Mol Carcinog, 2019 Aug. PMID 31020708, Free PMC Article
  5. Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination. Diarra Dit Konté N, et al. Nat Commun, 2017 Sep 21. PMID 28935965, Free PMC Article

See all (76) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review).
    Title: Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review).
  2. CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression.
    Title: CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression.
  3. Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA.
    Title: Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA.
  4. Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2.
    Title: Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2.
  5. MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway.
    Title: MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway.
  6. De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy.
    Title: De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy.
  7. miR-363-3p induces EMT via the Wnt/beta-catenin pathway in glioma cells by targeting CELF2.
    Title: miR-363-3p induces EMT via the Wnt/β-catenin pathway in glioma cells by targeting CELF2.
  8. LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression.
    Title: LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression.
  9. Genome-wide association analysis of cognitive function in Danish long-lived individuals.
    Title: Genome-wide association analysis of cognitive function in Danish long-lived individuals.
  10. LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein.
    Title: LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein.
Submit: New GeneRIF Correction See all GeneRIFs (41)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Developmental and epileptic encephalopathy 97
MedGen: C5561999 OMIM: 619561 GeneReviews: Not available
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EBI GWAS Catalog

Description
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
EBI GWAS Catalog
Genome-wide association study of liver enzymes in korean children.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pre-mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA processing TAS
Traceable Author Statement
more info
 PubMed 
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splice site recognition IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of heart contraction TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in Flemming body IDA
Inferred from Direct Assay
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
CUGBP Elav-like family member 2
Names
CUG triplet repeat RNA-binding protein 2
CUG-BP- and ETR-3-like factor 2
ELAV-type RNA-binding protein 3
KDM2B/CELF2 fusion
RNA-binding protein BRUNOL-3
bruno-like protein 3
neuroblastoma apoptosis-related RNA-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025076.2 → NP_001020247.1  CUGBP Elav-like family member 2 isoform 1

    See identical proteins and their annotated locations for NP_001020247.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1, also called NAPOR-1) contains a distinct 5' UTR, lacks an alternate segment in the 3' UTR, and uses an alternate splice site in the 3' coding region, compared to variant 3. The resulting isoform (3) is shorter, has a shorter N-terminus, and includes an alternate segment near the C-terminus, compared to isoform 3.
    Source sequence(s)
    AA595891, AF036956, AF090694, BC050635, BQ213648, CN356737, DA310511, DA819821
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Related
    ENSP00000404834.3, ENST00000417956.6
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  2. NM_001025077.3 → NP_001020248.1  CUGBP Elav-like family member 2 isoform 3

    See identical proteins and their annotated locations for NP_001020248.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3, also called NAPOR-3) represents the longest transcript and encodes isoform 3.
    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS44354.1
    UniProtKB/Swiss-Prot
    B7ZAN9, O95319, Q7KYU4, Q8N499, Q92950, Q96NW9, Q96RQ5, Q96RQ6, Q9UL67
    UniProtKB/TrEMBL
    B2RA86
    Related
    ENSP00000406451.2, ENST00000416382.6
    Conserved Domains (3) summary
    cd12638
    Location:416 → 507
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  3. NM_001083591.1 → NP_001077060.1  CUGBP Elav-like family member 2 isoform 4

    See identical proteins and their annotated locations for NP_001077060.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4, also called NAPOR-4) contains a distinct 5' UTR, lacks an alternate segment in the 3' UTR, and uses an alternate splice site in the 3' coding region, compared to variant 3. The resulting isoform (3) is shorter, has a shorter N-terminus, and includes an alternate segment near the C-terminus, compared to isoform 3.
    Source sequence(s)
    AA595891, AF090694, AF432906, BC050635, BQ213648, CN356737, CR976278, DA310511, DA819821
    Consensus CDS
    CCDS44356.1
    UniProtKB/TrEMBL
    Q5VZZ6
    Related
    ENSP00000476999.1, ENST00000608830.5
    Conserved Domains (3) summary
    cd12638
    Location:396 → 487
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  4. NM_001326317.2 → NP_001313246.1  CUGBP Elav-like family member 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL157704, AL583859, KF573678
    UniProtKB/TrEMBL
    B2RA86, B4DT00
    Conserved Domains (3) summary
    cd12638
    Location:392 → 483
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  5. NM_001326318.2 → NP_001313247.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL157704, AL583859, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  6. NM_001326319.2 → NP_001313248.1  CUGBP Elav-like family member 2 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL157704, AL583859, KF573678
    UniProtKB/TrEMBL
    Q5VZZ6

  7. NM_001326320.2 → NP_001313249.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL136452, AL157704, AL583859, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  8. NM_001326321.2 → NP_001313250.1  CUGBP Elav-like family member 2 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL157704, AL583859, KF573678
    UniProtKB/TrEMBL
    Q5VZZ6

  9. NM_001326323.2 → NP_001313252.1  CUGBP Elav-like family member 2 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136319, AL136320, AL136369, AL136452, AL157704, AL583859, KF573678
    UniProtKB/TrEMBL
    Q5VZZ6

  10. NM_001326324.2 → NP_001313253.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL136452, AL157704, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  11. NM_001326325.2 → NP_001313254.1  CUGBP Elav-like family member 2 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL136452, AL157704, KF573678
    UniProtKB/TrEMBL
    B2RA86

  12. NM_001326326.2 → NP_001313255.1  CUGBP Elav-like family member 2 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL136452, AL157704, KF573678
    Consensus CDS
    CCDS86070.1
    UniProtKB/TrEMBL
    A0A1B0GU44, B2RA86
    Related
    ENSP00000489955.1, ENST00000636488.1
    Conserved Domains (3) summary
    cd12638
    Location:428 → 519
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:51 → 134
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:143 → 223
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  13. NM_001326327.2 → NP_001313256.1  CUGBP Elav-like family member 2 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL136452, AL157704, KF573678
    Consensus CDS
    CCDS86069.1
    UniProtKB/TrEMBL
    A0A1B0GUN8, B2RA86
    Related
    ENSP00000490185.1, ENST00000637215.1
    Conserved Domains (4) summary
    TIGR01628
    Location:36 → 378
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:434 → 525
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:51 → 134
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:143 → 223
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  14. NM_001326328.2 → NP_001313257.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL136452, AL157704, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Related
    ENSP00000490401.1, ENST00000638035.1
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  15. NM_001326329.2 → NP_001313258.1  CUGBP Elav-like family member 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    UniProtKB/TrEMBL
    B2RA86, B4DT00
    Conserved Domains (3) summary
    cd12638
    Location:392 → 483
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  16. NM_001326330.2 → NP_001313259.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  17. NM_001326331.2 → NP_001313260.1  CUGBP Elav-like family member 2 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS86071.1
    UniProtKB/TrEMBL
    A0A0J9YX66, B4DS31
    Related
    ENSP00000488268.1, ENST00000631816.1
    Conserved Domains (4) summary
    TIGR01628
    Location:24 → 366
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:422 → 513
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  18. NM_001326332.2 → NP_001313261.1  CUGBP Elav-like family member 2 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS44354.1
    UniProtKB/Swiss-Prot
    B7ZAN9, O95319, Q7KYU4, Q8N499, Q92950, Q96NW9, Q96RQ5, Q96RQ6, Q9UL67
    UniProtKB/TrEMBL
    B2RA86
    Related
    ENSP00000488582.1, ENST00000631460.1
    Conserved Domains (3) summary
    cd12638
    Location:416 → 507
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  19. NM_001326333.2 → NP_001313262.1  CUGBP Elav-like family member 2 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    UniProtKB/Swiss-Prot
    O95319
    Conserved Domains (1) summary
    cd12638
    Location:194 → 285
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  20. NM_001326334.2 → NP_001313263.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  21. NM_001326335.2 → NP_001313264.1  CUGBP Elav-like family member 2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    UniProtKB/TrEMBL
    B4DS31
    Conserved Domains (3) summary
    cd12638
    Location:420 → 511
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  22. NM_001326336.2 → NP_001313265.1  CUGBP Elav-like family member 2 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    UniProtKB/TrEMBL
    Q5VZZ6

  23. NM_001326337.2 → NP_001313266.1  CUGBP Elav-like family member 2 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    UniProtKB/TrEMBL
    B4DS31
    Conserved Domains (3) summary
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12638
    Location:364 → 451
    RRM3_CELF1_2; RNA recognition motif 3 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  24. NM_001326338.2 → NP_001313267.1  CUGBP Elav-like family member 2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, KF573678
    Conserved Domains (4) summary
    cd12638
    Location:305 → 396
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    TIGR01661
    Location:15 → 392
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    cd12634
    Location:20 → 100
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cl17169
    Location:1 → 11
    RRM_SF; RNA recognition motif (RRM) superfamily

  25. NM_001326339.2 → NP_001313268.1  CUGBP Elav-like family member 2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, KF573678
    UniProtKB/TrEMBL
    B4DIB6, Q5VZZ6
    Conserved Domains (4) summary
    cd12638
    Location:311 → 402
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    TIGR01661
    Location:15 → 398
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    cd12634
    Location:20 → 100
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cl17169
    Location:1 → 11
    RRM_SF; RNA recognition motif (RRM) superfamily

  26. NM_001326340.2 → NP_001313269.1  CUGBP Elav-like family member 2 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    Consensus CDS
    CCDS86072.1
    UniProtKB/TrEMBL
    A0A0J9YXJ0, Q5VZZ6
    Related
    ENSP00000488422.1, ENST00000632065.1

  27. NM_001326341.2 → NP_001313270.1  CUGBP Elav-like family member 2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (3) summary
    cd12638
    Location:423 → 514
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  28. NM_001326342.2 → NP_001313271.1  CUGBP Elav-like family member 2 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    Consensus CDS
    CCDS44355.1
    UniProtKB/TrEMBL
    B2RA86, E9PC62
    Related
    ENSP00000488690.1, ENST00000633077.2
    Conserved Domains (4) summary
    TIGR01628
    Location:31 → 373
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:429 → 520
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  29. NM_001326343.2 → NP_001313272.1  CUGBP Elav-like family member 2 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    Q5VZZ6

  30. NM_001326344.2 → NP_001313273.1  CUGBP Elav-like family member 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    B2RA86, B4DT00
    Conserved Domains (3) summary
    cd12638
    Location:392 → 483
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  31. NM_001326345.2 → NP_001313274.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  32. NM_001326346.2 → NP_001313275.1  CUGBP Elav-like family member 2 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, KF573678
    UniProtKB/TrEMBL
    B4DM66, B4DZ01
    Conserved Domains (2) summary
    cd12638
    Location:188 → 279
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    TIGR01661
    Location:88 → 275
    ELAV_HUD_SF; ELAV/HuD family splicing factor

  33. NM_001326347.1 → NP_001313276.1  CUGBP Elav-like family member 2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704
    UniProtKB/TrEMBL
    B4DDE7, Q5VZZ6
    Related
    ENSP00000476656.1, ENST00000609692.5
    Conserved Domains (3) summary
    cd12638
    Location:404 → 495
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:23 → 106
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:115 → 195
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  34. NM_001326348.2 → NP_001313277.1  CUGBP Elav-like family member 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, KF573678
    UniProtKB/TrEMBL
    B2RA86, B4DT00
    Conserved Domains (3) summary
    cd12638
    Location:392 → 483
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  35. NM_001326349.2 → NP_001313278.1  CUGBP Elav-like family member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, KF573678
    Consensus CDS
    CCDS41488.1
    UniProtKB/TrEMBL
    B2RA86
    Related
    ENSP00000382743.3, ENST00000399850.7
    Conserved Domains (4) summary
    TIGR01628
    Location:1 → 342
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:398 → 489
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  36. NM_001394502.1 → NP_001381431.1  CUGBP Elav-like family member 2 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL136369, AL157704, KF573678
    Consensus CDS
    CCDS86071.1
    UniProtKB/TrEMBL
    A0A0J9YX66, B4DS31
    Conserved Domains (4) summary
    TIGR01628
    Location:24 → 366
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:422 → 513
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  37. NM_001394513.1 → NP_001381442.1  CUGBP Elav-like family member 2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (3) summary
    cd12638
    Location:423 → 514
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  38. NM_001394517.1 → NP_001381446.1  CUGBP Elav-like family member 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, KF573678
    UniProtKB/TrEMBL
    B2RA86, B4DT00
    Conserved Domains (3) summary
    cd12638
    Location:392 → 483
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:15 → 98
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:107 → 187
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  39. NM_001394518.1 → NP_001381447.1  CUGBP Elav-like family member 2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (3) summary
    cd12638
    Location:427 → 518
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  40. NM_001394519.1 → NP_001381448.1  CUGBP Elav-like family member 2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    UniProtKB/TrEMBL
    B2RA86
    Conserved Domains (3) summary
    cd12638
    Location:427 → 518
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  41. NM_006561.4 → NP_006552.3  CUGBP Elav-like family member 2 isoform 2

    See identical proteins and their annotated locations for NP_006552.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2, also called NAPOR-2) contains a distinct 5' UTR, lacks an alternate segment in the 3' UTR, and uses an alternate splice site in the 3' coding region, compared to variant 3. The resulting isoform (2) is longer, has a distinct N-terminus, and includes an alternate segment near the C-terminus, compared to isoform 3.
    Source sequence(s)
    AC026887, AL136320, AL157704, AL162408, KF573678
    Consensus CDS
    CCDS44355.1
    UniProtKB/TrEMBL
    B2RA86, E9PC62
    Related
    ENSP00000443926.1, ENST00000542579.5
    Conserved Domains (4) summary
    TIGR01628
    Location:31 → 373
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    cd12638
    Location:429 → 520
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:46 → 129
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:138 → 218
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    10462550..11336675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424494.1 → XP_047280450.1  CUGBP Elav-like family member 2 isoform X8

  2. XM_047424490.1 → XP_047280446.1  CUGBP Elav-like family member 2 isoform X8

  3. XM_047424501.1 → XP_047280457.1  CUGBP Elav-like family member 2 isoform X9

  4. XM_047424485.1 → XP_047280441.1  CUGBP Elav-like family member 2 isoform X4

  5. XM_047424484.1 → XP_047280440.1  CUGBP Elav-like family member 2 isoform X4

  6. XM_047424482.1 → XP_047280438.1  CUGBP Elav-like family member 2 isoform X1

  7. XM_047424483.1 → XP_047280439.1  CUGBP Elav-like family member 2 isoform X2

  8. XM_047424496.1 → XP_047280452.1  CUGBP Elav-like family member 2 isoform X8

  9. XM_047424492.1 → XP_047280448.1  CUGBP Elav-like family member 2 isoform X8

  10. XM_047424491.1 → XP_047280447.1  CUGBP Elav-like family member 2 isoform X8

  11. XM_047424499.1 → XP_047280455.1  CUGBP Elav-like family member 2 isoform X8

  12. XM_047424487.1 → XP_047280443.1  CUGBP Elav-like family member 2 isoform X6

  13. XM_047424506.1 → XP_047280462.1  CUGBP Elav-like family member 2 isoform X12

  14. XM_047424488.1 → XP_047280444.1  CUGBP Elav-like family member 2 isoform X7

  15. XM_047424508.1 → XP_047280464.1  CUGBP Elav-like family member 2 isoform X14

  16. XM_047424493.1 → XP_047280449.1  CUGBP Elav-like family member 2 isoform X8

  17. XM_047424500.1 → XP_047280456.1  CUGBP Elav-like family member 2 isoform X8

  18. XM_024447776.2 → XP_024303544.1  CUGBP Elav-like family member 2 isoform X3

    UniProtKB/TrEMBL
    B4DS31
    Conserved Domains (3) summary
    cd12638
    Location:426 → 517
    RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
    cd12631
    Location:39 → 122
    RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
    cd12634
    Location:131 → 211
    RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

  19. XM_047424495.1 → XP_047280451.1  CUGBP Elav-like family member 2 isoform X8

  20. XM_047424486.1 → XP_047280442.1  CUGBP Elav-like family member 2 isoform X5

  21. XM_047424507.1 → XP_047280463.1  CUGBP Elav-like family member 2 isoform X13

  22. XM_047424502.1 → XP_047280458.1  CUGBP Elav-like family member 2 isoform X9

  23. XM_047424505.1 → XP_047280461.1  CUGBP Elav-like family member 2 isoform X11

    UniProtKB/TrEMBL
    B4DT00

  24. XM_047424504.1 → XP_047280460.1  CUGBP Elav-like family member 2 isoform X10

  25. XM_047424503.1 → XP_047280459.1  CUGBP Elav-like family member 2 isoform X9

    Related
    ENSP00000487802.1, ENST00000632728.1

  26. XM_047424498.1 → XP_047280454.1  CUGBP Elav-like family member 2 isoform X8

  27. XM_047424489.1 → XP_047280445.1  CUGBP Elav-like family member 2 isoform X8

  28. XM_047424509.1 → XP_047280465.1  CUGBP Elav-like family member 2 isoform X15

  29. XM_047424510.1 → XP_047280466.1  CUGBP Elav-like family member 2 isoform X16

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    10472957..11348760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054364593.1 → XP_054220568.1  CUGBP Elav-like family member 2 isoform X8

  2. XM_054364589.1 → XP_054220564.1  CUGBP Elav-like family member 2 isoform X8

  3. XM_054364583.1 → XP_054220558.1  CUGBP Elav-like family member 2 isoform X4

  4. XM_054364582.1 → XP_054220557.1  CUGBP Elav-like family member 2 isoform X4

  5. XM_054364579.1 → XP_054220554.1  CUGBP Elav-like family member 2 isoform X1

  6. XM_054364580.1 → XP_054220555.1  CUGBP Elav-like family member 2 isoform X2

  7. XM_054364595.1 → XP_054220570.1  CUGBP Elav-like family member 2 isoform X8

  8. XM_054364586.1 → XP_054220561.1  CUGBP Elav-like family member 2 isoform X17

    UniProtKB/TrEMBL
    A0A1B0GU44

  9. XM_054364591.1 → XP_054220566.1  CUGBP Elav-like family member 2 isoform X8

  10. XM_054364590.1 → XP_054220565.1  CUGBP Elav-like family member 2 isoform X8

  11. XM_054364597.1 → XP_054220572.1  CUGBP Elav-like family member 2 isoform X8

  12. XM_054364585.1 → XP_054220560.1  CUGBP Elav-like family member 2 isoform X6

  13. XM_054364602.1 → XP_054220577.1  CUGBP Elav-like family member 2 isoform X12

  14. XM_054364587.1 → XP_054220562.1  CUGBP Elav-like family member 2 isoform X7

  15. XM_054364604.1 → XP_054220579.1  CUGBP Elav-like family member 2 isoform X14

  16. XM_054364592.1 → XP_054220567.1  CUGBP Elav-like family member 2 isoform X8

  17. XM_054364581.1 → XP_054220556.1  CUGBP Elav-like family member 2 isoform X3

  18. XM_054364594.1 → XP_054220569.1  CUGBP Elav-like family member 2 isoform X8

  19. XM_054364584.1 → XP_054220559.1  CUGBP Elav-like family member 2 isoform X5

  20. XM_054364603.1 → XP_054220578.1  CUGBP Elav-like family member 2 isoform X13

  21. XM_054364598.1 → XP_054220573.1  CUGBP Elav-like family member 2 isoform X9

  22. XM_054364601.1 → XP_054220576.1  CUGBP Elav-like family member 2 isoform X11

    UniProtKB/TrEMBL
    B4DT00

  23. XM_054364600.1 → XP_054220575.1  CUGBP Elav-like family member 2 isoform X10

  24. XM_054364599.1 → XP_054220574.1  CUGBP Elav-like family member 2 isoform X9

  25. XM_054364596.1 → XP_054220571.1  CUGBP Elav-like family member 2 isoform X8

  26. XM_054364588.1 → XP_054220563.1  CUGBP Elav-like family member 2 isoform X8

  27. XM_054364605.1 → XP_054220580.1  CUGBP Elav-like family member 2 isoform X15

  28. XM_054364606.1 → XP_054220581.1  CUGBP Elav-like family member 2 isoform X16

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O95319.1 GenPept UniProtKB/Swiss-Prot:O95319

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