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OR7E12P olfactory receptor family 7 subfamily E member 12 pseudogene [ Homo sapiens (human) ]

Gene ID: 10821, updated on 17-Jun-2024

Summary

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Official Symbol
OR7E12Pprovided by HGNC
Official Full Name
olfactory receptor family 7 subfamily E member 12 pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:8383
See related
Ensembl:ENSG00000189398 AllianceGenome:HGNC:8383
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HG1058; OR11-3; OST021; OR7E58P; OR7E79P; OR7E81P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

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See OR7E12P in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (3390707..3391915, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (3436106..3437314, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (3411937..3413145, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 56 pseudogene Neighboring gene zinc finger protein 195 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:3400077-3400640 Neighboring gene tumor suppressing subtransferable candidate 2 (pseudogene) Neighboring gene Sharpr-MPRA regulatory region 4578 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:3425235-3426069 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:3426070-3426903 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:3427261-3427774 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:3427775-3428286 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:3430516-3431016 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:3431017-3431517 Neighboring gene family with sequence similarity 86, member A pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3077 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3078 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3079 Neighboring gene MPRA-validated peak1172 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:3456375-3456993 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:3458797-3458965 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 15 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:3480157-3480658 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:3480659-3481158 Neighboring gene uncharacterized LOC105376526

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organization and evolution of olfactory receptor genes on human chromosome 11. Buettner JA, et al. Genomics, 1998 Oct 1. PMID 9787077
  2. Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Robertson NG, et al. Genomics, 1994 Sep 1. PMID 7829101
  3. DEFOG: a practical scheme for deciphering families of genes. Fuchs T, et al. Genomics, 2002 Sep. PMID 12213199

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • olfactory receptor, family 7, subfamily E, member 58 pseudogene
  • olfactory receptor, family 7, subfamily E, member 79 pseudogene
  • olfactory receptor, family 7, subfamily E, member 81 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_044999.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC123788
    Related
    ENST00000344740.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    3390707..3391915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    3436106..3437314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_002179.2: Suppressed sequence

    Description
    NG_002179.2: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
Nucleotide Protein
Heading Accession and Version

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