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LOC109280078 VISTA enhancer mm755 [ Mus musculus (house mouse) ]

Gene ID: 109280078, updated on 9-Aug-2024

Summary

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Gene symbol
LOC109280078
Gene description
VISTA enhancer mm755
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mm755; Rr1434
Summary
This locus represents a conserved genomic element that can function as an enhancer. It can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic hindbrain, limb and facial mesenchyme of transgenic mice. This locus also includes an enhancer that was validated by the STARR-seq (self-transcribing active regulatory region sequencing) reporter assay in metastable (SL) mouse embryonic stem cells, where it was defined as a C1 class enhancer that overlaps an active chromatin signature. [provided by RefSeq, Jul 2023]
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Genomic context

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See LOC109280078 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (29681387..29685090)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (29462413..29466116)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5586 Neighboring gene STARR-positive B cell enhancer ABC_E7508 Neighboring gene STARR-positive B cell enhancer ABC_E10944 Neighboring gene FYVE, RhoGEF and PH domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_42277 Neighboring gene STARR-seq mESC enhancer starr_42278 Neighboring gene STARR-positive B cell enhancer ABC_E2478 Neighboring gene STARR-positive B cell enhancer ABC_E8664 Neighboring gene VISTA enhancer mm81 Neighboring gene STARR-positive B cell enhancer mm9_chr17:29574287-29574588 Neighboring gene predicted gene, 36486 Neighboring gene predicted gene, 36199 Neighboring gene STARR-seq mESC enhancer starr_42287 Neighboring gene predicted gene, 26885 Neighboring gene STARR-positive B cell enhancer ABC_E2479 Neighboring gene STARR-positive B cell enhancer ABC_E5587 Neighboring gene STARR-positive B cell enhancer ABC_E8946 Neighboring gene STARR-positive B cell enhancer ABC_E9949 Neighboring gene proviral integration site 1 Neighboring gene transmembrane 217B Neighboring gene transmembrane protein 217

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. VISTA Enhancer Browser--a database of tissue-specific human enhancers. Visel A, et al. Nucleic Acids Res, 2007 Jan. PMID 17130149, Free PMC Article
  2. STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells. Peng T, et al. Genome Biol, 2020 Sep 10. PMID 32912294, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-seq mESC enhancer starr_42289
  • regulatory region 1434

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054347.1 

    Range
    101..3804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    29681387..29685090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version