LOC110120887 VISTA enhancer hs513 [Homo sapiens (human)] - Gene

Summary

Gene symbol: LOC110120887
Gene description: VISTA enhancer hs513
Gene type: biological region
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: This locus represents a conserved genomic element that can function as an enhancer. A subregion can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic cranial nerve and dorsal root ganglion of transgenic mice. Another overlapping subregion was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating DNase matched - State 8:EnhW, candidate weak enhancer and open chromatin) and K562 cells (group: K562 Activating DNase unmatched - State 12:CtcfO, distal CTCF/candidate insulator with open chromatin). [provided by RefSeq, Jul 2021]
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Annotation release	Status	Assembly	Chr	Location
110	latest, but not current	GRCh38.p14 (GCF_000001405.40)	10	NC_000010.11 (101780423..101781446)
110	latest, but not current	T2T-CHM13v2.0 (GCF_009914755.1)	10	NC_060934.1 (102663918..102664941)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	10	NC_000010.10 (103540180..103541203)