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PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110408748, updated on 15-Mar-2024

Summary

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Gene symbol
PLEKHG5
Gene description
pleckstrin homology and RhoGEF domain containing G5
See related
Ensembl:ENSNMEG00000004816
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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See PLEKHG5 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
26
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 20 NC_034428.1 (596774..609368)

Chromosome 20 - NC_034428.1Genomic Context describing neighboring genes Neighboring gene taste 1 receptor member 1 Neighboring gene nucleolar protein 9 Neighboring gene TNF receptor superfamily member 25 Neighboring gene espin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034428.1 Chromosome 20 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endothelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endocytic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family G member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034428.1 Reference NumMel1.0 Primary Assembly

    Range
    596774..609368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021417801.1 → XP_021273476.1  pleckstrin homology domain-containing family G member 5 isoform X3

    Related
    ENSNMET00000007822.1
    Conserved Domains (3) summary
    cd00160
    Location:323 → 512
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13244
    Location:569 → 667
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cl00155
    Location:85 → 144
    UBQ; Ubiquitin-like proteins

  2. XM_021417798.1 → XP_021273473.1  pleckstrin homology domain-containing family G member 5 isoform X2

    Conserved Domains (3) summary
    cd00160
    Location:422 → 611
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13244
    Location:668 → 766
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam14776
    Location:49 → 115
    UNC-79; Cation-channel complex subunit UNC-79

  3. XM_021417799.1 → XP_021273474.1  pleckstrin homology domain-containing family G member 5 isoform X3

    Conserved Domains (3) summary
    cd00160
    Location:323 → 512
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13244
    Location:569 → 667
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cl00155
    Location:85 → 144
    UBQ; Ubiquitin-like proteins

  4. XM_021417800.1 → XP_021273475.1  pleckstrin homology domain-containing family G member 5 isoform X3

    Conserved Domains (3) summary
    cd00160
    Location:323 → 512
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13244
    Location:569 → 667
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    cl00155
    Location:85 → 144
    UBQ; Ubiquitin-like proteins

  5. XM_021417797.1 → XP_021273472.1  pleckstrin homology domain-containing family G member 5 isoform X1

    Conserved Domains (2) summary
    cd00160
    Location:317 → 506
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13244
    Location:563 → 661
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
Nucleotide Protein
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