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Gng10 G protein subunit gamma 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 114119, updated on 2-Nov-2024

Summary

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Symbol
Gng10provided by RGD
Full Name
G protein subunit gamma 10provided by RGD
Primary source
RGD:621514
See related
EnsemblRapid:ENSRNOG00000025040 AllianceGenome:RGD:621514
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hg3m1
Summary
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Part of heterotrimeric G-protein complex. Orthologous to human GNG10 (G protein subunit gamma 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 425.2), Spleen (RPKM 413.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gng10 in Genome Data Viewer
Location:
5q24
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (78651167..78658060)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (73856124..73863017)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (76182100..76189014)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478984 Neighboring gene prostaglandin reductase 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C25 Neighboring gene U2 spliceosomal RNA Neighboring gene shortage in chiasmata 1 Neighboring gene uncharacterized LOC134486939 Neighboring gene uncharacterized LOC102550849

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Heterotypic tubular connections at the endoplasmic reticulum-Golgi complex interface. Vivero-Salmerón G, et al. Histochem Cell Biol, 2008 Oct. PMID 18648846
  2. Distribution of heterotrimeric G-protein beta and gamma subunits in the rat brain. Betty M, et al. Neuroscience, 1998 Jul. PMID 9622245
  3. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Xiao HS, et al. Proc Natl Acad Sci U S A, 2002 Jun 11. PMID 12060780, Free PMC Article
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC124511

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of heterotrimeric G-protein complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
Names
guanine nucleotide binding protein (G protein), gamma 10
guanine nucleotide binding protein 10
guanine nucleotide binding protein gamma 10 subunit
heterotrimeric guanine nucleotide-binding protein 3m1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053660.2 → NP_446112.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

    See identical proteins and their annotated locations for NP_446112.1

    Status: VALIDATED

    Source sequence(s)
    CB326556, CB616034, FQ214425
    UniProtKB/TrEMBL
    Q3KRE3
    Related
    ENSRNOP00000110602.1, ENSRNOT00000020707.9
    Conserved Domains (1) summary
    cd00068
    Location:7 → 63
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    78651167..78658060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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